Gene Symbol |
GAL3ST4
|
Entrez Gene |
79690
|
Alt Symbol |
GAL3ST-4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
galactose-3-O-sulfotransferase 4
|
Other Description |
beta-galactose-3-O-sulfotransferase 4|beta-galactose-3-O-sulfotransferase, 4|gal-beta-1,3-GalNAc 3'-sulfotransferase|galbeta1-3GalNAc 3'-sulfotransferase
|
Swissprots |
B4DWL8 Q8N3P7 Q96RP7 D6W5U5 Q96E33 A4D2A8 Q8WZ17 Q9HA78
|
Accessions |
EAL23847 EAW76575 EAW76577 EAW76579 Q96RP7 AF289575 AAL55759 AF316113 AAK73365 AK022178 BAB13977 AK092367 BAG52541 AK225890 AK301591 BAG63080 AL833824 CAD38686 BC012976 AAH12976 BM889458 NM_024637 NP_078913
|
Function |
Catalyzes the transfer of sulfate to beta-1,3-linked galactose residues in O-linked glycoproteins. Good substrates include asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc. {ECO:0000269|PubMed:11333265}.
|
Subcellular Location |
Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
Tissue Specificity |
Expressed mainly in placenta, thymus, testis, ovary, spinal cord, trachea and adrenal gland and at low levels in brain, lung, spleen, prostate, small intestine, colon, stomach thyroid and lymph node. {ECO:0000269|PubMed:11333265}.
|