Gene Symbol |
WOL
|
Entrez Gene |
814714
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Alt Symbol |
AHK4, ARABIDOPSIS HISTIDINE KINASE 4, ATCRE1, CRE1, CYTOKININ RESPONSE 1, T23K3.2, T23K3_2, WOL1, WOODEN LEG, WOODEN LEG 1
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Species |
Arabidopsis thaliana
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Gene Type |
protein-coding
|
Description |
histidine kinase 4
|
Other Description |
-
|
Swissprots |
Q9FDZ3 Q9C5U0 Q9C5T9 Q9C5T8 A5YY75 A5YY60 Q9SIT0
|
Accessions |
AAD21777 AEC05505 AEC05506 AEC05507 Q9C5U0 AB046871 BAB40776 AJ278528 CAC18521 AJ278529 CAC18522 AJ278530 CAC18523 NM_126244 NP_565277 NM_179594 NP_849925 NM_201667 NP_973396
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Function |
Cytokinins (CK) receptor related to bacterial two- component regulators. Binds also the synthetic urea-type cytokinin thiadiazuron, a potent defoliant and herbicide. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. In the presence of cytokinin, feed phosphate to phosphorelay-integrating histidine phosphotransfer protein (HPt) and activates subsequent cascade. In the absence of cytokinin, removes phosphate from HPt proteins, decreasing the system phosphoload. Involved in meristems establishment in seedlings. Acts as a redundant negative regulator of drought and salt stress responses, and abscisic acid (ABA) signaling in a cytokinin-dependent manner. Required to set vascular asymmetric cell divisions that establish phloem and procambi
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Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:21709172}; Multi-pass membrane protein {ECO:0000269|PubMed:21709172}.
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Tissue Specificity |
Mostly expressed in roots, specifically in the vascular cylinder and pericycle, and, to a lower extent, in leaves and flowers. Present in seedlings. {ECO:0000269|PubMed:11114883, ECO:0000269|PubMed:11230578, ECO:0000269|PubMed:15155880, ECO:0000269|PubMed:15166290}.
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Top Pathways |
Plant hormone signal transduction
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