| Gene Symbol |
KIR2DL5A
|
| Entrez Gene |
57292
|
| Alt Symbol |
CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
|
| Other Description |
killer cell immunoglobulin-like receptor 2DL5A|killer cell immunoglobulin-like receptor KIR2DL5A|killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5|killer-cell Ig-like receptor
|
| Swissprots |
Q8N109
|
| Accessions |
AAF74055 AAG40152 ABK97618 ABM92655 ABR88101 ABR88102 ABR88105 ABR88108 ABW04729 ABW04730 ACD49724 ACD49725 ACY78691 ACY78696 ACZ59814 ADI95449 ADJ78346 ADJ94650 AFV74773 CAD67581 CAG25965 CAG25966 CAJ29894 Q8N109 AF204903 AAF72845 AF217487 AAG37101 BC160063 AAI60063 NM_020535 NP_065396
|
| Function |
Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Natural killer cell mediated cytotoxicity, Graft-versus-host disease, Antigen processing and presentation
|
![Western Blot: KIR2DL5A Overexpression Lysate (Adult Normal) [NBP2-06630] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KIR2DL5A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2089_KIR2DL5A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06630-img0001.jpg)