Gene Symbol | Fdft1 |
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Entrez Gene | 14137 |
Alt Symbol | SQS, SS |
Species | Mouse |
Gene Type | protein-coding |
Description | farnesyl diphosphate farnesyl transferase 1 |
Other Description | FPP:FPP farnesyltransferase|farnesyl-diphosphate farnesyltransferase|squalene synthase |
Swissprots | Q8BPF5 P53798 |
Accessions | EDL36069 P53798 AK076062 BAC36156 AK136159 AK146766 BAE27418 AK158633 BAE34590 AK162294 BAE36836 AK168629 BAE40489 AK169317 BAE41072 AK183967 AK215831 AK217297 BC054722 AAH54722 BC138301 AAI38302 BC138302 AAI38303 D29016 BAA06102 XM_006518546 XP_006518609 XM_006518547 XP_006518610 XM_011244951 XP_011243253 NM_010191 NP_034321 |
Function | Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Top Pathways | Steroid biosynthesis |
Squalene synthetase CRISPR/Cas9 KO Plasmid (m) - sc-420311 from Santa Cruz Biotechnology
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Squalene synthetase HDR Plasmid (m) - sc-420311-HDR from Santa Cruz Biotechnology
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Squalene synthetase Double Nickase Plasmid (m) - sc-420311-NIC from Santa Cruz Biotechnology
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Squalene synthetase Double Nickase Plasmid (m2) - sc-420311-NIC-2 from Santa Cruz Biotechnology
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Squalene synthetase CRISPR Activation Plasmid (m) - sc-420311-ACT from Santa Cruz Biotechnology
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Squalene synthetase CRISPR Activation Plasmid (m2) - sc-420311-ACT-2 from Santa Cruz Biotechnology
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Squalene synthetase Lentiviral Activation Particles (m) - sc-420311-LAC from Santa Cruz Biotechnology
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Squalene synthetase Lentiviral Activation Particles (m2) - sc-420311-LAC-2 from Santa Cruz Biotechnology
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Squalene synthetase siRNA (m) - sc-61611 from Santa Cruz Biotechnology
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Squalene synthetase shRNA Plasmid (m) - sc-61611-SH from Santa Cruz Biotechnology
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Squalene synthetase shRNA (m) Lentiviral Particles - sc-61611-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU091371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN31310 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31310 from Sigma-Aldrich
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FDFT1 siRNA (Mouse) - CRM1330 from Cohesion Biosciences
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FDFT1 - MBS8207023 from MyBioSource
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shRNA set against Mouse FDFT1 (NM_010191.2) - SHH293925 from Creative biogene
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shRNA set against Mouse Fdft1(NM_010191.2) - SHH055253 from Creative biogene
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FDFT1 shRNA Plasmid (Mouse) - CHM1330 from Cohesion Biosciences
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FDFT1 miRNA 3'UTR clone - MiUTR1M-04660 from Creative biogene
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