Gene Symbol | MBD5 |
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Entrez Gene | 55777 |
Alt Symbol | MRD1 |
Species | Human |
Gene Type | protein-coding |
Description | methyl-CpG binding domain protein 5 |
Other Description | methyl-CpG-binding domain protein 5|methyl-CpG-binding protein MBD5 |
Swissprots | A5HMQ4 A7E2B1 Q9NUV6 Q9P267 Q53SR1 |
Accessions | AAY14912 EAX11550 EAX11551 EAX11552 Q9P267 AB040894 BAA95985 AK055079 AK090496 BAG52172 AK304424 BAG65253 BC014534 BC150264 AAI50265 CA449443 DA240785 EF542797 ABQ18300 XM_005263711 XP_005263768 XM_011511470 XP_011509772 XM_011511471 XP_011509773 XM_011511472 XP_011509774 XM_011511473 XP_011509775 XM_011511474 XP_011509776 XM_011511475 XP_011509777 XM_011511476 XP_011509778 XR_922967 NM_018328 NP_060798 |
Function | Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro). |
Subcellular Location | Isoform 1: Nucleus. Chromosome. Note=Associated with pericentric heterochromatin. |
Tissue Specificity | Detected in heart, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:12529184}. |
MBD5 CRISPR/Cas9 KO Plasmid (h) - sc-410031 from Santa Cruz Biotechnology
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MBD5 HDR Plasmid (h) - sc-410031-HDR from Santa Cruz Biotechnology
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MBD5 Double Nickase Plasmid (h) - sc-410031-NIC from Santa Cruz Biotechnology
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MBD5 Double Nickase Plasmid (h2) - sc-410031-NIC-2 from Santa Cruz Biotechnology
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MBD5 CRISPR Activation Plasmid (h) - sc-410031-ACT from Santa Cruz Biotechnology
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MBD5 CRISPR Activation Plasmid (h2) - sc-410031-ACT-2 from Santa Cruz Biotechnology
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MBD5 Lentiviral Activation Particles (h) - sc-410031-LAC from Santa Cruz Biotechnology
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MBD5 Lentiviral Activation Particles (h2) - sc-410031-LAC-2 from Santa Cruz Biotechnology
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MBD5 siRNA (h) - sc-94756 from Santa Cruz Biotechnology
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MBD5 shRNA Plasmid (h) - sc-94756-SH from Santa Cruz Biotechnology
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MBD5 shRNA (h) Lentiviral Particles - sc-94756-V from Santa Cruz Biotechnology
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MBD5 RNAi - H00055777-R01 from Novus Biologicals
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MISSION® esiRNA - EHU126281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13079 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13079 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04827 from Sigma-Aldrich
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MBD5 siRNA (Human) - CRJ0912 from Cohesion Biosciences
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shRNA set against Human MBD5 (NM_018328.4) - SHH338811 from Creative biogene
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Human MBD5 siRNA - orb271413 from Biorbyt
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MBD5 shRNA Plasmid (Human) - CHJ0912 from Cohesion Biosciences
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MBD5 miRNA 3'UTR clone - MiUTR3H-11915 from Creative biogene
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