Gene Symbol | DEFA6 |
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Entrez Gene | 1671 |
Alt Symbol | DEF6, HD-6 |
Species | Human |
Gene Type | protein-coding |
Description | defensin, alpha 6, Paneth cell-specific |
Other Description | defensin 6|defensin-6 |
Swissprots | Q6EZF9 Q01524 |
Accessions | AAC50382 AAT68876 EAW80484 Q01524 BC069667 AAH69667 BC069710 AAH69710 BC069728 AAH69728 BC069769 AAH69769 BC093951 AAH93951 BC093953 AAH93953 BM855691 HQ448454 ADQ32934 M98331 AAB59357 NM_001926 NP_001917 |
Function | Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1. {ECO:0000269|PubMed:15616305, ECO:0000269|PubMed:17088326}. |
Subcellular Location | Secreted. |
Tissue Specificity | Paneth cells of the small intestine. |
α-defensin 6 CRISPR/Cas9 KO Plasmid (h) - sc-410758 from Santa Cruz Biotechnology
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α-defensin 6 HDR Plasmid (h) - sc-410758-HDR from Santa Cruz Biotechnology
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α-defensin 6 Double Nickase Plasmid (h) - sc-410758-NIC from Santa Cruz Biotechnology
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α-defensin 6 Double Nickase Plasmid (h2) - sc-410758-NIC-2 from Santa Cruz Biotechnology
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α-defensin 6 CRISPR Activation Plasmid (h) - sc-410758-ACT from Santa Cruz Biotechnology
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α-defensin 6 CRISPR Activation Plasmid (h2) - sc-410758-ACT-2 from Santa Cruz Biotechnology
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α-defensin 6 Lentiviral Activation Particles (h) - sc-410758-LAC from Santa Cruz Biotechnology
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α-defensin 6 Lentiviral Activation Particles (h2) - sc-410758-LAC-2 from Santa Cruz Biotechnology
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α-defensin 6 siRNA (h) - sc-105018 from Santa Cruz Biotechnology
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α-defensin 6 shRNA Plasmid (h) - sc-105018-SH from Santa Cruz Biotechnology
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α-defensin 6 shRNA (h) Lentiviral Particles - sc-105018-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7089 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7089 from Sigma-Aldrich
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DEFA6 siRNA (Human) - CRH1180 from Cohesion Biosciences
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DEFA6 - MBS8235237 from MyBioSource
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shRNA set against Human Defa (NM_001926.3) - SHH276329 from Creative biogene
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Human DEFA6 siRNA - orb261682 from Biorbyt
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DEFA6 shRNA Plasmid (Human) - CHH1180 from Cohesion Biosciences
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DEFA6 miRNA 3'UTR clone - MiUTR4H-TG02659 from Creative biogene
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