| Gene Symbol |
FASTK
|
| Entrez Gene |
10922
|
| Alt Symbol |
FAST
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Fas-activated serine/threonine kinase
|
| Other Description |
FAST kinase|fas-activated serine/threonine kinase
|
| Swissprots |
A8K867 F8VTW9 Q8IVA0 Q14296 Q59EM8
|
| Accessions |
EAL24499 EAL24500 EAW54033 EAW54034 EAW54035 EAW54036 EAW54037 EAW54038 EAW54039 EAW54040 EAW54041 EAW54042 EAW54043 Q14296 AB209783 BAD93020 AK023141 BAB14425 AK223132 BAD96852 AK292232 BAF84921 AL713798 CAH10616 BC000377 AAH00377 BC006386 BC011770 AAH11770 BC039026 AAH39026 BM799420 BU682096 DA253544 DQ892922 ABM83848 DQ896171 ABM87170 EU176731 ABW03532 F02420 X86779 CAA60448 XM_005249932 XP_005249989 XM_005249933 XP_005249990 XM_011515760 XP_011514062 XM_011515761 XP_011514063 XM_011515762 XP_011514064 XM_011515763 XP_011514065 NM_001258461 NP_001245390 NM_006712 NP_006703 NM_033015 NP_148936
|
| Function |
Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor. {ECO:0000269|PubMed:17135269, ECO:0000269|PubMed:7544399}.
|
| Tissue Specificity |
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
|
![Western Blot: FASTK Overexpression Lysate (Adult Normal) [NBL1-10602] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FASTK.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6144_FASTK%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10602-img0002.jpg)