Gene Symbol | NUDT2 |
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Entrez Gene | 318 |
Alt Symbol | APAH1 |
Species | Human |
Gene Type | protein-coding |
Description | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
Other Description | Ap4A hydrolase 1|Ap4Aase|bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)|bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]|diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase|diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase|diadenosine tetraphosphatase|nucleoside diphosphate-linked moiety X motif 2|nudix motif 2 |
Swissprots | Q5T589 D3DRM0 P50583 |
Accessions | EAW58461 EAW58462 EAW58463 P50583 AA310093 AA398857 AK310574 BC004926 AAH04926 BG622439 BG825757 BM802700 BQ007098 DN992111 DQ892973 ABM83899 DQ896221 ABM87220 U30313 AAC50277 NM_001161 NP_001152 NM_001244390 NP_001231319 NM_147172 NP_671701 NM_147173 NP_671702 |
Function | Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. Plays a major role in maintaining homeostasis. |
Top Pathways | Purine metabolism, Pyrimidine metabolism |
AP4A Hydrolase CRISPR/Cas9 KO Plasmid (h) - sc-407028 from Santa Cruz Biotechnology
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AP4A Hydrolase HDR Plasmid (h) - sc-407028-HDR from Santa Cruz Biotechnology
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AP4A Hydrolase Double Nickase Plasmid (h) - sc-407028-NIC from Santa Cruz Biotechnology
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AP4A Hydrolase Double Nickase Plasmid (h2) - sc-407028-NIC-2 from Santa Cruz Biotechnology
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AP4A Hydrolase CRISPR Activation Plasmid (h) - sc-407028-ACT from Santa Cruz Biotechnology
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AP4A Hydrolase CRISPR Activation Plasmid (h2) - sc-407028-ACT-2 from Santa Cruz Biotechnology
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AP4A Hydrolase Lentiviral Activation Particles (h) - sc-407028-LAC from Santa Cruz Biotechnology
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AP4A Hydrolase Lentiviral Activation Particles (h2) - sc-407028-LAC-2 from Santa Cruz Biotechnology
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AP4A Hydrolase siRNA (h) - sc-60188 from Santa Cruz Biotechnology
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AP4A Hydrolase shRNA Plasmid (h) - sc-60188-SH from Santa Cruz Biotechnology
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AP4A Hydrolase shRNA (h) Lentiviral Particles - sc-60188-V from Santa Cruz Biotechnology
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NUDT2 RNAi - H00000318-R03 from Novus Biologicals
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NUDT2 RNAi - H00000318-R01 from Novus Biologicals
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MISSION® esiRNA - EHU160451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15599 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15599 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02842 from Sigma-Aldrich
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NUDT2 siRNA (Human) - CRH0219 from Cohesion Biosciences
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NUDT2 RNAi - H00000318-R02 from Novus Biologicals
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shRNA set against Human NUDT2 (NM_001161.4) - SHH356148 from Creative biogene
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AP4A Hydrolase CRISPR/Cas9 KO Plasmid (h2) - sc-407028-KO-2 from Santa Cruz Biotechnology
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AP4A Hydrolase HDR Plasmid (h2) - sc-407028-HDR-2 from Santa Cruz Biotechnology
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Human NUDT2 siRNA - orb260721 from Biorbyt
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NUDT2 shRNA Plasmid (Human) - CHH0219 from Cohesion Biosciences
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NUDT2 miRNA 3'UTR clone - MiUTR3H-05345 from Creative biogene
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