| Gene Symbol |
KIAA1598
|
| Entrez Gene |
57698
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
KIAA1598
|
| Other Description |
shootin-1|shootin1
|
| Swissprots |
B3KTJ7 B7Z7Z9 B3KRD3 B3KTJ8 Q68DG1 Q9NUV0 Q9HCH4 A8MYU7 B3KRH2 B3KTE0 A0MZ66 B4E3U1 Q6PIM5
|
| Accessions |
A0MZ66 EAW49434 EAW49435 EAW49436 EAW49437 EAW49438 AB046818 BAB13424 AK001984 BAA92019 AK091381 BAG52345 AK091410 AK091578 BAG52384 AK092331 AK095419 BAG53052 AK095703 BAG53109 AK095709 BAG53110 AK124745 AK302705 BAH13785 AK304865 BAG65603 AL157479 BC022348 AAH22348 BC032303 AAH32303 BE348500 BE897523 BI086871 BX537593 BX648065 CR749417 CAH18259 CX783645 DA241212 DC402821 DN993119 EF055487 ABK56022 H17869 XM_005270002 XP_005270059 XM_006717931 XP_006717994 NM_001127211 NP_001120683 NM_001258298 NP_001245227 NM_001258299 NP_001245228 NM_001258300 NP_001245229 NM_018330 NP_060800
|
| Function |
Involved in the generation of internal asymmetric signals required for neuronal polarization. Acts upstream of PI3K (phosphoinositide 3-kinase), by being required for spatially localized PI3K activity. Accumulates asymmetrically in a single neurite before polarization, leading to axon induction for polarization, its absence from the nascent axon's siblings by competition preventing the formation of surplus axons (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell projection, axon {ECO:0000250}.
|