HSD17B7

Gene Symbol HSD17B7
Entrez Gene 51478
Alt Symbol PRAP, SDR37C1
Species Human
Gene Type protein-coding
Description hydroxysteroid (17-beta) dehydrogenase 7
Other Description 17 beta-hydroxysteroid dehydrogenase type VII|17-beta-HSD 7|17-beta-hydroxysteroid dehydrogenase 7|17beta hydroxysteroid dehydrogenase|3-keto-steroid reductase|estradiol 17-beta-dehydrogenase 7|short chain dehydrogenase/reductase family 37C member 1|short chain dehydrogenase/reductase family 37C, member 1
Swissprots Q9UF00 Q8WWS2 Q7Z4V9 Q5T246 P56937
Accessions AAF14537 CAC88111 EAW90716 EAW90720 EAW90721 EAW90725 P56937 AF098786 AAF09266 AF145023 AAP97275 AJ249179 CAC20418 AK022929 BAB14312 AK290741 BAF83430 AU129437 AW136392 AY358962 AAQ89321 BC007068 AAH07068 BC065246 AAH65246 BT007075 AAP35738 DB256037 GQ129366 ACT64500 GQ129367 ACT64501 XR_921829 XR_921830 NM_001304512 NP_001291441 NM_001304513 NP_001291442 NM_016371 NP_057455
Function Responsible for the reduction of the keto group on the C-3 of sterols. {ECO:0000269|PubMed:12829805}.
Subcellular Location Cell membrane; Single-pass membrane protein.
Tissue Specificity Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells.
Top Pathways Steroid hormone biosynthesis, Ovarian steroidogenesis, Steroid biosynthesis

17β-HSD7 (L-13) - sc-160117 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HSD17B7 antibody - ab112006 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HSD17B7 antibody (ab112006) at 1/500 dilutionLane 1 : 293T cell lysateLane 2 : MCF7 cell lysate

Anti-HSD17B7 antibody - ab69341 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-HSD17B7 antibody (ab69341) at 1/500 dilutionLane 1 : HSD17B7 transfected 293T lysateLane 2 : Non-transfected 293T lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-HSD17B7 antibody - ab122995 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HSD17B7 antibody (ab122995) at 1 µg/ml + PANC1 cell lysate at 10 µg

Anti-HSD17B7 antibody - N-terminal - ab175490 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HSD17B7 antibody - N-terminal (ab175490) at 1/1000 dilutionLane 1 : 293 cell line lysateLane 2 : HL60 cell line lysateLane 3 : Jurkat cell line lysateLysates/proteins at 35 µg per lane.

Anti-HSD17B7 / PRAP Antibody (aa57-85) - LS-C165038 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of HSD17B7 Antibody in 293,HL-60,Jurkat cell line lysates (35 ug/lane). HSD17B7 (arrow) was detected using the purified antibody.(2 ug/ml)

Anti-HSD17B7 / PRAP Antibody - LS-C308325 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HSD17B7 / PRAP Antibody (aa255-342) - LS-C308330 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HSD17B7 / PRAP Antibody - LS-C311234 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B7 / PRAP Antibody - LS-C311235 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD17B7 / PRAP Antibody (aa35-221) - LS-C178565 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD17B7 / PRAP Antibody (aa160-209) - LS-C145936 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HSD17B7 antibody LS-C145936 Western blot of PANC1 Cell lysate. Antibody concentration 1 ug/ml.

HSD17B7 Antibody - H00051478-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: HSD17B7 Antibody [H00051478-B01P] - Analysis of HSD17B7 expression in transfected 293T cell line by HSD17B7 polyclonal antibody.  Lane1:HSD17B7 transfected lysate(37.51 KDa). Lane2:Non-transfected lysate.

HSD17B7 Antibody - H00051478-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HSD17B7 Antibody [H00051478-D01P] - Analysis of HSD17B7 expression in transfected 293T cell line by HSD17B7 polyclonal antibody.Lane 1: HSD17B7 transfected lysate(38.20 KDa).Lane 2: Non-transfected lysate.

HSD17B7 Antibody (1G10) - H00051478-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G10
Western Blot: HSD17B7 Antibody (1G10) [H00051478-M01] - HSD17B7 monoclonal antibody (M01), clone 1G10. Analysis of HSD17B7 expression in rat testis.

Monoclonal Anti-HSD17B7, (C-terminal) antibody produced in mouse - SAB1403250 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G10
<B>Immunofluorescence</B><BR/>Monoclonal Anti-HSD17B7: <B>Cat. No. SAB1403250</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-HSD17B7 antibody produced in rabbit - HPA047496 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HSD17B7:<B>Cat. No. HPA047496</B>: Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

Anti-HSD17B7 antibody produced in mouse - SAB1407493 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HSD17B7: <B>Cat. No. SAB1407493</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~37.5 kDa using HSD17B7 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

HSD17B7 antibody - middle region (ARP61842_P050) - ARP61842_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HSD17B7-Antibody-N-term - AP6760a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of HSD17B7 Antibody (N-term) (Cat. #AP6760a) in 293,HL-60,Jurkat cell line lysates (35ug/lane). HSD17B7 (arrow) was detected using the purified Pab.(2ug/ml)

HSD17B7 Antibody - N-terminal region (OAAB03842) - OAAB03842 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

HSD17B7 antibody, N-term - GTX81730 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-HSD17B7 antibody, N-term used in Flow cytometry/FACS. GTX81730

Hydroxysteroid (17-Beta) Dehydrogenase 7 Antibody - abx113091 from Abbexa

Host Rabbit
Clonality Polyclonal

17-beta HSD7 / HSD17B7 antibody - 16925-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of  paraffin-embedded human liver using 16925-1-AP(HSD17B7P2 antibody) at dilution of 1:50 (under 40x lens)

17-beta HSD7 / HSD17B7 (N-term) antibody - AP17485PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of HSD17B7 Antibody (N-term) (AP17485PU-N) in 293,HL-60,Jurkat cell line lysates (35ug/lane). HSD17B7 (arrow) was detected using the purified Pab.(2ug/ml)
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