Gene Symbol | HSD17B7 |
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Entrez Gene | 51478 |
Alt Symbol | PRAP, SDR37C1 |
Species | Human |
Gene Type | protein-coding |
Description | hydroxysteroid (17-beta) dehydrogenase 7 |
Other Description | 17 beta-hydroxysteroid dehydrogenase type VII|17-beta-HSD 7|17-beta-hydroxysteroid dehydrogenase 7|17beta hydroxysteroid dehydrogenase|3-keto-steroid reductase|estradiol 17-beta-dehydrogenase 7|short chain dehydrogenase/reductase family 37C member 1|short chain dehydrogenase/reductase family 37C, member 1 |
Swissprots | Q9UF00 Q8WWS2 Q7Z4V9 Q5T246 P56937 |
Accessions | AAF14537 CAC88111 EAW90716 EAW90720 EAW90721 EAW90725 P56937 AF098786 AAF09266 AF145023 AAP97275 AJ249179 CAC20418 AK022929 BAB14312 AK290741 BAF83430 AU129437 AW136392 AY358962 AAQ89321 BC007068 AAH07068 BC065246 AAH65246 BT007075 AAP35738 DB256037 GQ129366 ACT64500 GQ129367 ACT64501 XR_921829 XR_921830 NM_001304512 NP_001291441 NM_001304513 NP_001291442 NM_016371 NP_057455 |
Function | Responsible for the reduction of the keto group on the C-3 of sterols. {ECO:0000269|PubMed:12829805}. |
Subcellular Location | Cell membrane; Single-pass membrane protein. |
Tissue Specificity | Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells. |
Top Pathways | Steroid hormone biosynthesis, Ovarian steroidogenesis, Steroid biosynthesis |
17β-HSD7 (L-13) - sc-160117 from Santa Cruz Biotechnology
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Anti-HSD17B7 antibody - ab112006 from Abcam
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Anti-HSD17B7 antibody - ab69341 from Abcam
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Anti-HSD17B7 antibody - ab122995 from Abcam
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Anti-HSD17B7 antibody - N-terminal - ab175490 from Abcam
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Anti-HSD17B7 / PRAP Antibody (aa57-85) - LS-C165038 from LifeSpan Bioscience
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Anti-HSD17B7 / PRAP Antibody - LS-C308325 from LifeSpan Bioscience
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Anti-HSD17B7 / PRAP Antibody (aa255-342) - LS-C308330 from LifeSpan Bioscience
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Anti-HSD17B7 / PRAP Antibody - LS-C311234 from LifeSpan Bioscience
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Anti-HSD17B7 / PRAP Antibody - LS-C311235 from LifeSpan Bioscience
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Anti-HSD17B7 / PRAP Antibody (aa35-221) - LS-C178565 from LifeSpan Bioscience
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Anti-HSD17B7 / PRAP Antibody (aa160-209) - LS-C145936 from LifeSpan Bioscience
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HSD17B7 Antibody - H00051478-B01P from Novus Biologicals
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HSD17B7 Antibody - H00051478-D01P from Novus Biologicals
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HSD17B7 Antibody (1G10) - H00051478-M01 from Novus Biologicals
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Monoclonal Anti-HSD17B7, (C-terminal) antibody produced in mouse - SAB1403250 from Sigma-Aldrich
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Anti-HSD17B7 antibody produced in rabbit - HPA047496 from Sigma-Aldrich
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Anti-HSD17B7 antibody produced in mouse - SAB1407493 from Sigma-Aldrich
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HSD17B7 antibody - middle region (ARP61842_P050) - ARP61842_P050 from Aviva Systems Biology
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HSD17B7-Antibody-N-term - AP6760a from Abgent, a WuXi AppTec company
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HSD17B7 Antibody - N-terminal region (OAAB03842) - OAAB03842 from Aviva Systems Biology
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HSD17B7 antibody, N-term - GTX81730 from GeneTex
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Hydroxysteroid (17-Beta) Dehydrogenase 7 Antibody - abx113091 from Abbexa
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17-beta HSD7 / HSD17B7 antibody - 16925-1-AP from Acris Antibodies
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17-beta HSD7 / HSD17B7 (N-term) antibody - AP17485PU-N from Acris Antibodies
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