Gene Symbol | ZBTB33 |
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Entrez Gene | 10009 |
Alt Symbol | ZNF-kaiso, ZNF348 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger and BTB domain containing 33 |
Other Description | WUGSC:H_DJ525N14.1|kaiso transcription factor|transcriptional regulator Kaiso|zinc finger and BTB domain-containing protein 33 |
Swissprots | Q8N3P0 Q7Z361 O00319 B2R5U6 Q86T24 Q8IVP6 |
Accessions | AAB54087 CCQ43375 EAX11891 Q86T24 AK092998 AK094230 AK312321 BAG35243 AL833604 CAD91170 AL833856 CAD38715 AM393304 CAL38182 BC042753 AAH42753 BX538016 CAD97963 BX538101 CAD98016 DB468333 NM_001184742 NP_001171671 NM_006777 NP_006768 |
Function | Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. {ECO:0000269|PubMed:11445535, ECO:0000269|PubMed:14527417, ECO:0000269|PubMed:15548582, ECO:0000269|PubMed:15817151}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15781635}. Cytoplasm {ECO:0000269|PubMed:15781635}. Note=Also cytoplasmic in cells grown at high densities. |
Tissue Specificity | Expressed in vascular endothelium. {ECO:0000269|PubMed:14699141}. |
Human Kaiso full length protein - ab160762 from Abcam
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Human Kaiso protein fragment - ab160763 from Abcam
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ZBTB33 / Kaiso Antibody Blocking Peptide - LS-E13998 from LifeSpan Bioscience
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Recombinant Human Kaiso Protein - H00010009-P01 from Novus Biologicals
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Recombinant Human Kaiso Protein - H00010009-Q01 from Novus Biologicals
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ZBTB33-Antibody-Center-Blocking-Peptide - BP19593c from Abgent, a WuXi AppTec company
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ZBTB33 Blocking Peptide - 33R-5965 from Fitzgerald
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ZBTB33 - H00010009-P01-10 from Acris Antibodies
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ZBTB33 - H00010009-P01-25 from Acris Antibodies
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ZBTB33 - H00010009-Q01-10 from Acris Antibodies
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ZBTB33 - H00010009-Q01-25 from Acris Antibodies
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Recombinant Human Transcriptional regulator Kaiso(ZBTB33) - CSB-YP769768HU CSB-EP769768HU CSB-BP769768HU CSB-MP769768HU from Cusabio
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Kaiso Recombinant Protein Antigen - NBP1-87866PEP from Novus Biologicals
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Kaiso Recombinant Protein Antigen - NBP1-87865PEP from Novus Biologicals
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ZBTB33 Peptide, Human - M34GP17680H from Creative Peptides
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