Gene Symbol | TMCO1 |
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Entrez Gene | 54499 |
Alt Symbol | HP10122, PCIA3, PNAS-136, TMCC4 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane and coiled-coil domains 1 |
Other Description | putative membrane protein|transmembrane and coiled-coil domain-containing protein 1|transmembrane and coiled-coil domains 4|xenogeneic cross-immune protein PCIA3 |
Swissprots | Q9BZU8 Q9BZS3 B2REA0 O75545 Q9UM00 |
Accessions | EAW90762 EAW90763 EAW90764 EAW90765 Q9UM00 AB020980 BAA86974 AF070626 AAC25388 AF274935 AAK07514 AF277194 AAK07549 AI379550 AK298614 BAH12827 AK316080 BAH14451 AK316610 BAG38197 AY359027 AAQ89386 AY763589 AAV34755 BC000104 AAH00104 BG772940 BP257387 CN430121 NM_001256164 NP_001243093 NM_001256165 NP_001243094 NM_019026 NP_061899 NR_045818 |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10393320}; Multi-pass membrane protein {ECO:0000269|PubMed:10393320}. Golgi apparatus membrane {ECO:0000269|PubMed:10393320}; Multi-pass membrane protein {ECO:0000269|PubMed:10393320}. |
Tissue Specificity | Widely expressed in adult and fetal tissues, with higher levels in thymus, prostate, testis and small intestine and lower levels in brain, placenta, lung and kidney. {ECO:0000269|PubMed:10393320, ECO:0000269|PubMed:20018682}. |
TMCO1 CRISPR/Cas9 KO Plasmid (h) - sc-409963 from Santa Cruz Biotechnology
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TMCO1 HDR Plasmid (h) - sc-409963-HDR from Santa Cruz Biotechnology
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TMCO1 Double Nickase Plasmid (h) - sc-409963-NIC from Santa Cruz Biotechnology
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TMCO1 Double Nickase Plasmid (h2) - sc-409963-NIC-2 from Santa Cruz Biotechnology
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TMCO1 CRISPR Activation Plasmid (h) - sc-409963-ACT from Santa Cruz Biotechnology
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TMCO1 CRISPR Activation Plasmid (h2) - sc-409963-ACT-2 from Santa Cruz Biotechnology
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TMCO1 Lentiviral Activation Particles (h) - sc-409963-LAC from Santa Cruz Biotechnology
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TMCO1 Lentiviral Activation Particles (h2) - sc-409963-LAC-2 from Santa Cruz Biotechnology
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TMCO1 siRNA (h) - sc-88439 from Santa Cruz Biotechnology
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TMCO1 shRNA Plasmid (h) - sc-88439-SH from Santa Cruz Biotechnology
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TMCO1 shRNA (h) Lentiviral Particles - sc-88439-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU055251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21443 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21443 from Sigma-Aldrich
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TMCO1 siRNA (Human) - CRJ0097 from Cohesion Biosciences
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TMCO1 - MBS8236327 from MyBioSource
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shRNA set against Human TMCO1 (NM_019026.4) - SHH428460 from Creative biogene
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TMCO1 shRNA Plasmid (Human) - CHJ0097 from Cohesion Biosciences
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TMCO1 miRNA 3'UTR clone - MiUTR4H-TG09020 from Creative biogene
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