Gene Symbol | SPINT2 |
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Entrez Gene | 10653 |
Alt Symbol | DIAR3, HAI-2, HAI2, Kop, PB |
Species | Human |
Gene Type | protein-coding |
Description | serine peptidase inhibitor, Kunitz type, 2 |
Other Description | hepatocyte growth factor activator inhibitor type 2|kunitz-type protease inhibitor 2|placental bikunin|serine protease inhibitor, Kunitz type, 2 |
Swissprots | O00271 Q5TZQ3 B4DLU1 A8K667 O14895 Q969E0 O43291 |
Accessions | EAW56766 EAW56767 O43291 AB006534 BAA25024 AF027205 AAB84031 AI199013 AK127479 AK291532 BAF84221 AK297154 BAG59653 AW275313 AX772830 CAE06264 BC001668 AAH01668 BC007705 AAH07705 BC011951 AAH11951 BC011955 AAH11955 BC012868 AAH12868 BT020115 AAV38918 BT020116 AAV38919 BT020117 AAV38920 CR407604 CAG28532 DQ597458 U78095 AAC02781 Z36849 NM_001166103 NP_001159575 NM_021102 NP_066925 |
Function | Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea. |
HAI-2 CRISPR/Cas9 KO Plasmid (h) - sc-407762 from Santa Cruz Biotechnology
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HAI-2 HDR Plasmid (h) - sc-407762-HDR from Santa Cruz Biotechnology
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HAI-2 Double Nickase Plasmid (h) - sc-407762-NIC from Santa Cruz Biotechnology
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HAI-2 Double Nickase Plasmid (h2) - sc-407762-NIC-2 from Santa Cruz Biotechnology
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HAI-2 CRISPR Activation Plasmid (h) - sc-407762-ACT from Santa Cruz Biotechnology
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HAI-2 CRISPR Activation Plasmid (h2) - sc-407762-ACT-2 from Santa Cruz Biotechnology
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HAI-2 Lentiviral Activation Particles (h) - sc-407762-LAC from Santa Cruz Biotechnology
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HAI-2 Lentiviral Activation Particles (h2) - sc-407762-LAC-2 from Santa Cruz Biotechnology
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HAI-2 siRNA (h) - sc-39556 from Santa Cruz Biotechnology
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HAI-2 shRNA Plasmid (h) - sc-39556-SH from Santa Cruz Biotechnology
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HAI-2 shRNA (h) Lentiviral Particles - sc-39556-V from Santa Cruz Biotechnology
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HAI-2/SPINT2 RNAi - H00010653-R01 from Novus Biologicals
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MISSION® esiRNA - EHU143141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20491 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04345 from Sigma-Aldrich
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SPINT2 siRNA (Human) - CRH7261 from Cohesion Biosciences
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SPINT2 - MBS8236150 from MyBioSource
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shRNA set against Human SPINT2 (NM_021102.3) - SHH416876 from Creative biogene
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SPINT2 shRNA Plasmid (Human) - CHH7261 from Cohesion Biosciences
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SPINT2 miRNA 3'UTR clone - MiUTR3H-07392 from Creative biogene
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SPINT2 miRNA 3'UTR clone - MiUTR3H-07393 from Creative biogene
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