Gene Symbol | KRTAP10-7 |
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Entrez Gene | 386675 |
Alt Symbol | KAP10.7, KAP18.7, KRTAP18-7 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 10-7 |
Other Description | high sulfur keratin-associated protein 10.7|keratin associated protein 18-7|keratin-associated protein 10-7 |
Swissprots | Q0VDJ8 Q70LJ2 P60409 |
Accessions | EAX09413 P60409 AB076354 BAD01541 AJ566385 CAD97465 BC119643 AAI19644 NM_198689 NP_941962 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. {ECO:0000269|PubMed:14962103, ECO:0000269|PubMed:15028290}. |
KRTAP10-7 CRISPR/Cas9 KO Plasmid (h) - sc-415728 from Santa Cruz Biotechnology
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KRTAP10-7 HDR Plasmid (h) - sc-415728-HDR from Santa Cruz Biotechnology
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KRTAP10-7 Double Nickase Plasmid (h) - sc-415728-NIC from Santa Cruz Biotechnology
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KRTAP10-7 Double Nickase Plasmid (h2) - sc-415728-NIC-2 from Santa Cruz Biotechnology
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KRTAP10-7 CRISPR Activation Plasmid (h) - sc-415728-ACT from Santa Cruz Biotechnology
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KRTAP10-7 CRISPR Activation Plasmid (h2) - sc-415728-ACT-2 from Santa Cruz Biotechnology
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KRTAP10-7 Lentiviral Activation Particles (h) - sc-415728-LAC from Santa Cruz Biotechnology
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KRTAP10-7 Lentiviral Activation Particles (h2) - sc-415728-LAC-2 from Santa Cruz Biotechnology
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KRTAP10-7 siRNA (h) - sc-91489 from Santa Cruz Biotechnology
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KRTAP10-7 shRNA Plasmid (h) - sc-91489-SH from Santa Cruz Biotechnology
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KRTAP10-7 shRNA (h) Lentiviral Particles - sc-91489-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11423 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11423 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03861 from Sigma-Aldrich
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KRTAP10-7 siRNA (Human) - CRJ7711 from Cohesion Biosciences
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shRNA set against Human KRTAP10-7(NM_198689.2) - SHH138665 from Creative biogene
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KRTAP10-7 shRNA Plasmid (Human) - CHJ7711 from Cohesion Biosciences
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KRTAP10-7 miRNA 3'UTR clone - MiUTR1H-05483 from Creative biogene
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