Gene Symbol | AK1 |
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Entrez Gene | 203 |
Alt Symbol | HTL-S-58j |
Species | Human |
Gene Type | protein-coding |
Description | adenylate kinase 1 |
Other Description | AK 1|ATP-AMP transphosphorylase 1|ATP:AMP phosphotransferase|adenylate kinase isoenzyme 1|adenylate monophosphate kinase|myokinase|testis secretory sperm binding protein Li 58j |
Swissprots | Q9BVK9 P00568 Q9UQC7 |
Accessions | AAA51686 EAW87706 EAW87707 EAW87708 EAW87709 P00568 AB021871 BAA78534 AK223501 BAD97221 AK313758 BAG36497 BC001116 AAH01116 BC036803 BC100022 AAI00023 BT019580 AAV38387 CR541977 CAG46775 CR542004 CAG46801 DA077967 DQ892576 ABM83502 DQ895792 ABM86718 EU794628 ACJ13682 XM_005251786 XP_005251843 XM_011518348 XP_011516650 XM_011518349 XP_011516651 NM_000476 NP_000467 |
Function | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. {ECO:0000255|HAMAP-Rule:MF_03171, ECO:0000269|PubMed:23416111}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Purine metabolism |
AK1 CRISPR/Cas9 KO Plasmid (h) - sc-407286 from Santa Cruz Biotechnology
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AK1 HDR Plasmid (h) - sc-407286-HDR from Santa Cruz Biotechnology
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AK1 Double Nickase Plasmid (h) - sc-407286-NIC from Santa Cruz Biotechnology
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AK1 Double Nickase Plasmid (h2) - sc-407286-NIC-2 from Santa Cruz Biotechnology
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AK1 CRISPR Activation Plasmid (h) - sc-407286-ACT from Santa Cruz Biotechnology
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AK1 CRISPR Activation Plasmid (h2) - sc-407286-ACT-2 from Santa Cruz Biotechnology
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AK1 Lentiviral Activation Particles (h) - sc-407286-LAC from Santa Cruz Biotechnology
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AK1 Lentiviral Activation Particles (h2) - sc-407286-LAC-2 from Santa Cruz Biotechnology
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AK1 siRNA (h) - sc-38904 from Santa Cruz Biotechnology
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AK1 shRNA Plasmid (h) - sc-38904-SH from Santa Cruz Biotechnology
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AK1 shRNA (h) Lentiviral Particles - sc-38904-V from Santa Cruz Biotechnology
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Adenylate Kinase 1 RNAi - H00000203-R01V from Novus Biologicals
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Adenylate Kinase 1 RNAi - H00000203-R02 from Novus Biologicals
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MISSION® esiRNA - EHU008801 from Sigma-Aldrich
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MISSION® siRNA - SIHK0074 from Sigma-Aldrich
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MISSION® siRNA - SIHK0073 from Sigma-Aldrich
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MISSION® siRNA - SIHK0075 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2994 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2994 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09646 from Sigma-Aldrich
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AK1 siRNA (Human) - CRH0140 from Cohesion Biosciences
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AK1 - MBS8218055 from MyBioSource
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shRNA set against Human AK1 (NM_000476.2) - SHH234078 from Creative biogene
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shRNA set against Human AK1(NM_000476.2) - SHG049213 from Creative biogene
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Human AK1 siRNA - orb260642 from Biorbyt
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