Gene Symbol | NDUFB1 |
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Entrez Gene | 4707 |
Alt Symbol | CI-MNLL, CI-SGDH, MNLL |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1|NADH-ubiquinone oxidoreductase MNLL subunit|complex I MNLL subunit|complex I-MNLL |
Swissprots | O75438 A0AV68 |
Accessions | EAW81476 EAW81477 EAW81478 EAW81479 O75438 AF050638 AAD42054 AK055348 AK316557 BAG48175 BC009691 AAH09691 BC104672 AAI04673 BC126232 AAI26233 BC126234 AAI26235 BM052981 BX476462 HQ258048 ADR82802 NM_004545 NP_004536 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB1 CRISPR/Cas9 KO Plasmid (h) - sc-410899 from Santa Cruz Biotechnology
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NDUFB1 HDR Plasmid (h) - sc-410899-HDR from Santa Cruz Biotechnology
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NDUFB1 Double Nickase Plasmid (h) - sc-410899-NIC from Santa Cruz Biotechnology
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NDUFB1 Double Nickase Plasmid (h2) - sc-410899-NIC-2 from Santa Cruz Biotechnology
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NDUFB1 CRISPR Activation Plasmid (h) - sc-410899-ACT from Santa Cruz Biotechnology
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NDUFB1 CRISPR Activation Plasmid (h2) - sc-410899-ACT-2 from Santa Cruz Biotechnology
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NDUFB1 Lentiviral Activation Particles (h) - sc-410899-LAC from Santa Cruz Biotechnology
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NDUFB1 Lentiviral Activation Particles (h2) - sc-410899-LAC-2 from Santa Cruz Biotechnology
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NDUFB1 siRNA (h) - sc-92336 from Santa Cruz Biotechnology
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NDUFB1 shRNA Plasmid (h) - sc-92336-SH from Santa Cruz Biotechnology
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NDUFB1 shRNA (h) Lentiviral Particles - sc-92336-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU122371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15153 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15153 from Sigma-Aldrich
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NDUFB1 siRNA (Human) - CRH3121 from Cohesion Biosciences
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NDUFB1 RNAi - H00004707-R01 from Novus Biologicals
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shRNA set against Human NDUFB1 (NM_004545.3) - SHH350684 from Creative biogene
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shRNA set against Human NDUFB1(NM_004545.3) - SHR005044 from Creative biogene
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Human NDUFB1 siRNA - orb263623 from Biorbyt
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NDUFB1 shRNA Plasmid (Human) - CHH3121 from Cohesion Biosciences
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NDUFB1 miRNA 3'UTR clone - MiUTR1H-06701 from Creative biogene
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