| Gene Symbol |
Glud1
|
| Entrez Gene |
14661
|
| Alt Symbol |
AI118167, Gdh-X, Glud, Gludl
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
glutamate dehydrogenase 1
|
| Other Description |
GDH 1|glutamate dehydrogenase 1, mitochondrial
|
| Swissprots |
Q8C273 P26443
|
| Accessions |
EDL24875 P26443 AK075971 AK089152 BAC40767 AK150637 AK161876 BAE36618 AK181205 AK207576 AK209048 AK213533 AK213994 AK217090 AK219236 AK219431 BC052724 AAH52724 BC057347 AAH57347 EF437367 X57024 CAA40341 NM_008133 NP_032159
|
| Function |
Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. {ECO:0000269|PubMed:23663782}.
|
| Subcellular Location |
Mitochondrion matrix.
|
| Top Pathways |
Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, D-Glutamine and D-glutamate metabolism
|