| Gene Symbol |
SEC23IP
|
| Entrez Gene |
11196
|
| Alt Symbol |
MSTP053, P125, P125A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SEC23 interacting protein
|
| Other Description |
SEC23-interacting protein
|
| Swissprots |
Q8IXH5 D3DRD2 Q9Y6Y8 Q9BUK5
|
| Accessions |
EAW49371 EAW49372 EAW49373 EAW49374 Q9Y6Y8 AB019435 BAA77392 AF116723 AAO15299 AI093198 AK000698 AK001135 BAG50859 AK021846 AK023238 BAG51172 AK301517 BAG63023 AK307286 AK314592 BC002540 BC063800 AAH63800 BT006755 AAP35401 BX649119 DA193345 DA942854 XM_005269469 XP_005269526 XM_005269470 XP_005269527 XR_246061 NM_007190 NP_009121 NR_037771
|
| Function |
Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P). {ECO:0000269|PubMed:10400679, ECO:0000269|PubMed:15623529, ECO:0000269|PubMed:22922100}.
|
| Subcellular Location |
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle. {ECO:0000269|PubMed:10400679}.
|
![Western Blot: SEC23IP Overexpression Lysate (Adult Normal) [NBL1-15780] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SEC23IP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1940_SEC23IP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15780-img0002.jpg)