Gene Symbol | C12orf65 |
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Entrez Gene | 91574 |
Alt Symbol | COXPD7, SPG55 |
Species | Human |
Gene Type | protein-coding |
Description | chromosome 12 open reading frame 65 |
Other Description | probable peptide chain release factor C12orf65, mitochondrial |
Swissprots | Q8WUC6 Q9H3J6 |
Accessions | EAW98395 EAW98396 Q9H3J6 AF061733 AAG43144 AK025908 AK095982 BAC04665 AK126043 BC018145 AAH18145 BC020885 AAH20885 BC062329 AAH62329 BI850864 BU507560 HQ448204 ADQ32685 XM_005253630 XP_005253687 XM_011538980 XP_011537282 XM_011538981 XP_011537283 XM_011538982 XP_011537284 NM_001143905 NP_001137377 NM_001194995 NP_001181924 NM_152269 NP_689482 |
Function | May act as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion. May help rescuing stalled mitoribosomes during translation (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:20186120}. |
C12orf65 CRISPR/Cas9 KO Plasmid (h) - sc-413900 from Santa Cruz Biotechnology
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C12orf65 HDR Plasmid (h) - sc-413900-HDR from Santa Cruz Biotechnology
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C12orf65 Double Nickase Plasmid (h) - sc-413900-NIC from Santa Cruz Biotechnology
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C12orf65 Double Nickase Plasmid (h2) - sc-413900-NIC-2 from Santa Cruz Biotechnology
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C12orf65 CRISPR Activation Plasmid (h) - sc-413900-ACT from Santa Cruz Biotechnology
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C12orf65 CRISPR Activation Plasmid (h2) - sc-413900-ACT-2 from Santa Cruz Biotechnology
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C12orf65 Lentiviral Activation Particles (h) - sc-413900-LAC from Santa Cruz Biotechnology
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C12orf65 Lentiviral Activation Particles (h2) - sc-413900-LAC-2 from Santa Cruz Biotechnology
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C12orf65 siRNA (h) - sc-96107 from Santa Cruz Biotechnology
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C12orf65 shRNA Plasmid (h) - sc-96107-SH from Santa Cruz Biotechnology
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C12orf65 shRNA (h) Lentiviral Particles - sc-96107-V from Santa Cruz Biotechnology
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C12orf65 RNAi - H00091574-R01 from Novus Biologicals
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MISSION® esiRNA - EHU103881 from Sigma-Aldrich
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MISSION® esiRNA - EHU142521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4273 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4273 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07263 from Sigma-Aldrich
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C12orf65 siRNA (Human) - CRJ4050 from Cohesion Biosciences
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C12orf65 - MBS8209130 from MyBioSource
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shRNA set against Human C12orf65 (NM_152269.4) - SHH249182 from Creative biogene
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Human C12orf65 siRNA - orb274551 from Biorbyt
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C12orf65 shRNA Plasmid (Human) - CHJ4050 from Cohesion Biosciences
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C12ORF65 miRNA 3'UTR clone - MiUTR3H-12944 from Creative biogene
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C12ORF65 miRNA 3'UTR clone - MiUTR3H-12945 from Creative biogene
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