| Gene Symbol |
Gabarapl1
|
| Entrez Gene |
57436
|
| Alt Symbol |
3110025G09Rik, 9130422N19Rik, AI196471, Apg8l, Atg8l, GECI, MNCb-0091
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
|
| Other Description |
GABA(A) receptor-associated protein like 1|GABA(A) receptor-associated protein-like 1|GEC-1|gamma-aminobutyric acid receptor-associated protein-like 1|glandular epithelial cell protein 1
|
| Swissprots |
Q9JJ97 Q3TJB9 Q3TG14 Q3TXZ5 Q8R3R8
|
| Accessions |
EDK99932 EDK99933 EDK99934 Q8R3R8 AB041648 BAA95100 AF180518 AAK16236 AK006103 AK011975 BAB27950 AK014083 BAB29146 AK015049 BAB29690 AK018687 BAB31345 AK159015 BAE34769 AK167500 BAE39576 AK168921 BAE40734 AK182413 AK186960 AK191751 AK214264 BC004602 AAH04602 BC024706 AAH24706 NM_020590 NP_065615
|
| Function |
Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, autophagosome {ECO:0000250}.
|
| Tissue Specificity |
Expressed in testis and heart at high levels. {ECO:0000269|PubMed:11414770}.
|
| Top Pathways |
GABAergic synapse, Regulation of autophagy
|