Gene Symbol | ACP5 |
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Entrez Gene | 54 |
Alt Symbol | SPENCDI, TRAP |
Species | Human |
Gene Type | protein-coding |
Description | acid phosphatase 5, tartrate resistant |
Other Description | TrATPase|tartrate-resistant acid ATPase|tartrate-resistant acid phosphatase type 5 |
Swissprots | A8K3V2 Q2TAB1 Q9UCJ7 Q9UCJ5 Q6IAS6 P13686 Q9UCJ6 |
Accessions | CAV30742 EAW84232 EAW84233 EAW84234 P13686 AK225912 AK290717 BAF83406 AK307164 BC025414 AAH25414 BC111014 AAI11015 BM708166 BP367008 BX365007 CR457078 CAG33359 EU831755 ACE87273 HQ447785 ADQ32269 J04430 AAA76849 X14618 CAA32771 XM_005259938 XP_005259995 XM_005259939 XP_005259996 XM_011528069 XP_011526371 NM_001111034 NP_001104504 NM_001111035 NP_001104505 NM_001111036 NP_001104506 NM_001611 NP_001602 |
Function | Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias. |
Subcellular Location | Lysosome. |
Top Pathways | Lysosome, Osteoclast differentiation, Rheumatoid arthritis, Riboflavin metabolism |
TRAP CRISPR/Cas9 KO Plasmid (h) - sc-400892 from Santa Cruz Biotechnology
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TRAP HDR Plasmid (h) - sc-400892-HDR from Santa Cruz Biotechnology
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TRAP Double Nickase Plasmid (h) - sc-400892-NIC from Santa Cruz Biotechnology
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TRAP Double Nickase Plasmid (h2) - sc-400892-NIC-2 from Santa Cruz Biotechnology
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TRAP CRISPR Activation Plasmid (h) - sc-400892-ACT from Santa Cruz Biotechnology
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TRAP CRISPR Activation Plasmid (h2) - sc-400892-ACT-2 from Santa Cruz Biotechnology
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TRAP Lentiviral Activation Particles (h) - sc-400892-LAC from Santa Cruz Biotechnology
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TRAP Lentiviral Activation Particles (h2) - sc-400892-LAC-2 from Santa Cruz Biotechnology
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TRAP siRNA (h) - sc-44164 from Santa Cruz Biotechnology
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TRAP shRNA Plasmid (h) - sc-44164-SH from Santa Cruz Biotechnology
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TRAP shRNA (h) Lentiviral Particles - sc-44164-V from Santa Cruz Biotechnology
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ACP5 RNAi - H00000054-R01 from Novus Biologicals
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MISSION® esiRNA - EHU052921 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0913 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0007 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0009 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0008 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0914 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2739 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2739 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03191 from Sigma-Aldrich
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ACP5 siRNA (Human) - CRH0042 from Cohesion Biosciences
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ACP5 - MBS8230262 from MyBioSource
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shRNA set against Human ACP5 (NM_001611.3) - SHH230574 from Creative biogene
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shRNA set against Human ACP5(NM_001611.3) - SHG030907 from Creative biogene
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