| Gene Symbol |
PGM3
|
| Entrez Gene |
5238
|
| Alt Symbol |
AGM1, IMD23, PAGM, PGM 3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphoglucomutase 3
|
| Other Description |
N-acetylglucosamine-phosphate mutase 1|acetylglucosamine phosphomutase|phosphoacetylglucosamine mutase
|
| Swissprots |
E1P547 O95394 Q9UFV5 Q9NS94 E9PF86 B2RB65 Q5JWR4 Q9UIY2 Q96J46 Q9NTT6 Q9H8G5 B4DX94 D6RF12
|
| Accessions |
EAW48667 EAW48668 EAW48669 EAW48670 EAW48671 O95394 AB032081 BAB00613 AF102265 AAC72409 AF180371 AAD55097 AK001365 AK021676 AK023432 BAG51190 AK023685 AK023709 BAB14652 AK225363 AK301867 BAG63306 AK314512 BAG37112 AL117443 CAB55928 BC001258 AAH01258 DB004046 DB033430 XM_011535901 XP_011534203 XM_011535902 XP_011534204 XM_011535903 XP_011534205 XR_942476 XR_942477 XR_942478 XR_942479 XR_942480 NM_001199917 NP_001186846 NM_001199918 NP_001186847 NM_001199919 NP_001186848 NM_015599 NP_056414
|
| Function |
Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation. {ECO:0000303|PubMed:24589341, ECO:0000303|PubMed:24698316, ECO:0000303|PubMed:24931394}.
|
| Tissue Specificity |
Found in many tissues except lung. Relatively high expression in pancreas, heart, liver, and placenta, and relatively low expression in brain, skeletal muscle and kidney. {ECO:0000269|PubMed:10721701}.
|
| Top Pathways |
Amino sugar and nucleotide sugar metabolism
|
![Western Blot: PGM3 Overexpression Lysate (Adult Normal) [NBL1-14340] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PGM3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8007_PGM3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14340-img0002.jpg)