| Gene Symbol | chd |
|---|---|
| Entrez Gene | 30161 |
| Alt Symbol | chordino, wu:fe47d04 |
| Species | Zebrafish |
| Gene Type | protein-coding |
| Description | chordin |
| Other Description | din|dino (din)|fe47d04|protein chordino |
| Swissprots | Q9DED8 O57472 |
| Accessions | BAB18642 O57472 AF034606 AAB93485 BC162594 AAI62594 NM_130973 NP_571048 |
| Function | Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted {ECO:0000250}. |
| Tissue Specificity | During gastrulation, levels are highest in the organizer region. Also present in the developing brain and in paraxial mesoderm and ectoderm. {ECO:0000269|PubMed:9441687}. |
| Top Pathways | TGF-beta signaling pathway |