| Gene Symbol |
chd
|
| Entrez Gene |
30161
|
| Alt Symbol |
chordino, wu:fe47d04
|
| Species |
Zebrafish
|
| Gene Type |
protein-coding
|
| Description |
chordin
|
| Other Description |
din|dino (din)|fe47d04|protein chordino
|
| Swissprots |
Q9DED8 O57472
|
| Accessions |
BAB18642 O57472 AF034606 AAB93485 BC162594 AAI62594 NM_130973 NP_571048
|
| Function |
Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted {ECO:0000250}.
|
| Tissue Specificity |
During gastrulation, levels are highest in the organizer region. Also present in the developing brain and in paraxial mesoderm and ectoderm. {ECO:0000269|PubMed:9441687}.
|
| Top Pathways |
TGF-beta signaling pathway
|