Gene Symbol | ADARB2 |
---|---|
Entrez Gene | 105 |
Alt Symbol | ADAR3, RED2 |
Species | Human |
Gene Type | protein-coding |
Description | adenosine deaminase, RNA-specific, B2 (non-functional) |
Other Description | RED2 homolog|RNA-dependent adenosine deaminase 3|RNA-editing deaminase 2|RNA-editing enzyme 2|adenosine deaminase, RNA-specific, B2 (RED1 homolog rat)|adenosine deaminase, RNA-specific, B2 (RED2 homolog rat)|double-stranded RNA-specific editase B2|dsRNA adenosine deaminase B2|homolog of rat BLUE |
Swissprots | Q5VW42 Q9NS39 Q5VUT6 B2RPJ5 |
Accessions | EAW86508 Q9NS39 AF034837 AAF78094 AI695657 AK055107 BAG51468 AK057763 AK094294 AK123334 AK289895 BAF82584 AK307451 AK308579 BC047443 AAH47443 BC137477 AAI37478 BC139725 AAI39726 BC140852 AAI40853 DA533361 XR_930468 NM_018702 NP_061172 |
Function | Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA. |
Subcellular Location | Nucleus. |
Tissue Specificity | Brain specific. Expressed at higher levels in astrocytomas as compared to the normal brain tissue. {ECO:0000269|PubMed:10836796, ECO:0000269|PubMed:18178553}. |
ADAR3 CRISPR/Cas9 KO Plasmid (h) - sc-402742 from Santa Cruz Biotechnology
|
||||||||
ADAR3 HDR Plasmid (h) - sc-402742-HDR from Santa Cruz Biotechnology
|
||||||||
ADAR3 Double Nickase Plasmid (h) - sc-402742-NIC from Santa Cruz Biotechnology
|
||||||||
ADAR3 Double Nickase Plasmid (h2) - sc-402742-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ADAR3 CRISPR Activation Plasmid (h) - sc-402742-ACT from Santa Cruz Biotechnology
|
||||||||
ADAR3 CRISPR Activation Plasmid (h2) - sc-402742-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ADAR3 Lentiviral Activation Particles (h) - sc-402742-LAC from Santa Cruz Biotechnology
|
||||||||
ADAR3 Lentiviral Activation Particles (h2) - sc-402742-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ADAR3 siRNA (h) - sc-37663 from Santa Cruz Biotechnology
|
||||||||
ADAR3 shRNA Plasmid (h) - sc-37663-SH from Santa Cruz Biotechnology
|
||||||||
ADAR3 shRNA (h) Lentiviral Particles - sc-37663-V from Santa Cruz Biotechnology
|
||||||||
RED2 RNAi - H00000105-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU146351 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN2849 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2849 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR08095 from Sigma-Aldrich
|
||||||||
ADARB2 siRNA (Human) - CRH0069 from Cohesion Biosciences
|
||||||||
ADARB2 - MBS8218739 from MyBioSource
|
||||||||
ADARB2 shRNA Plasmid (Human) - CHH0069 from Cohesion Biosciences
|