Gene Symbol | CHST11 |
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Entrez Gene | 50515 |
Alt Symbol | C4ST, C4ST-1, C4ST1, HSA269537 |
Species | Human |
Gene Type | protein-coding |
Description | carbohydrate (chondroitin 4) sulfotransferase 11 |
Other Description | C4S-1|IgH/CHST11 fusion|carbohydrate sulfotransferase 11|chondroitin 4-O-sulfotransferase 1 |
Swissprots | Q9NY36 A8K4F8 Q9NXY6 Q9NPF2 |
Accessions | EAW97748 EAW97749 EAW97750 Q9NPF2 AB042326 BAA95485 AF131762 AF239820 AAF81691 AJ269537 CAB87380 AJ289134 CAB92134 AK123676 AK290923 BAF83612 AK313217 AL833176 AY533204 AAU87522 AY533205 AAU87523 BC013315 AAH13315 BC030271 BC061524 DA853534 HQ447191 ADQ31678 NM_001173982 NP_001167453 NM_018413 NP_060883 |
Function | Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6- di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed. Highly expressed in spleen, thymus, bone marrow, peripheral blood leukocytes, lymph node, heart, brain, lung and placenta. {ECO:0000269|PubMed:10781601, ECO:0000269|PubMed:11056388}. |
Top Pathways | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |
Human CHST11 protein fragment - ab153322 from Abcam
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CHST11 Antibody Blocking Peptide - LS-E17197 from LifeSpan Bioscience
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Recombinant Human CHST11 Protein - H00050515-Q01 from Novus Biologicals
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Human C4S-1 protein - orb138551 from Biorbyt
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Chst11 Blocking Peptide - 33R-2875 from Fitzgerald
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CHST11 - H00050515-Q01-10 from Acris Antibodies
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CHST11 - H00050515-Q01-25 from Acris Antibodies
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CHST11 fusion protein - Ag8875 from Proteintech Group
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CHST11 fusion protein - ag8725 from Proteintech Group
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Recombinant Human CHST11, His-tagged - CHST11-11224H from Creative Biomart
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Recombinant Human CHST11, His tagged - CHST11-148H from Creative Biomart
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Human CHST11 / C4ST-1 Protein (His Tag) - 11396-H08B-100 from Sino Biological
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Recombinant Human Carbohydrate sulfotransferase 11(CHST11) - CSB-YP882066HU CSB-EP882066HU CSB-BP882066HU CSB-MP882066HU from Cusabio
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Recombinant Human CHST11 / C4ST-1 Protein (His tag) - PKSH031132 from Elabscience
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CHST11 Recombinant Protein Antigen - NBP2-30481PEP from Novus Biologicals
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CHST11-Blocking-Peptide-Center - BP21059a from Abgent, a WuXi AppTec company
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CHST11 Peptide, Human - M34GP03146H from Creative Peptides
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Human CHST11 / C4ST-1 Protein (His Tag) - 11396-H08B from ABclonal
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CHST11 / C4ST-1, Recombinant Protein - MBS2545792 from MyBioSource
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