Gene Symbol | GBE1 |
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Entrez Gene | 2632 |
Alt Symbol | APBD, GBE, GSD4 |
Species | Human |
Gene Type | protein-coding |
Description | glucan (1,4-alpha-), branching enzyme 1 |
Other Description | 1,4-alpha-glucan-branching enzyme|amylo-(1,4 to 1,6) transglucosidase|amylo-(1,4 to 1,6) transglycosylase|brancher enzyme|glycogen branching enzyme|glycogen-branching enzyme |
Swissprots | Q04446 Q96EN0 B3KWV3 |
Accessions | CCQ42971 EAW68879 EAW68880 Q04446 AB209731 BAD92968 AK125918 BAG54265 AK297939 BAG60255 AK300620 BAG62313 AK312245 BC012098 AAH12098 BE614098 BM509929 BQ022720 BQ632568 EU176342 ABW03793 L07956 AAA58642 NM_000158 NP_000149 |
Function | Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells. |
Tissue Specificity | Highest levels found in liver and muscle. |
Top Pathways | Starch and sucrose metabolism |
GBE1 CRISPR/Cas9 KO Plasmid (h) - sc-408730 from Santa Cruz Biotechnology
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GBE1 HDR Plasmid (h) - sc-408730-HDR from Santa Cruz Biotechnology
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GBE1 Double Nickase Plasmid (h) - sc-408730-NIC from Santa Cruz Biotechnology
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GBE1 Double Nickase Plasmid (h2) - sc-408730-NIC-2 from Santa Cruz Biotechnology
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GBE1 CRISPR Activation Plasmid (h) - sc-408730-ACT from Santa Cruz Biotechnology
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GBE1 CRISPR Activation Plasmid (h2) - sc-408730-ACT-2 from Santa Cruz Biotechnology
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GBE1 Lentiviral Activation Particles (h) - sc-408730-LAC from Santa Cruz Biotechnology
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GBE1 Lentiviral Activation Particles (h2) - sc-408730-LAC-2 from Santa Cruz Biotechnology
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GBE1 siRNA (h) - sc-78413 from Santa Cruz Biotechnology
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GBE1 shRNA Plasmid (h) - sc-78413-SH from Santa Cruz Biotechnology
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GBE1 shRNA (h) Lentiviral Particles - sc-78413-V from Santa Cruz Biotechnology
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GBE1 RNAi - H00002632-R01 from Novus Biologicals
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MISSION® esiRNA - EHU132131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1639 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1639 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06770 from Sigma-Aldrich
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GBE1 siRNA (Human) - CRH1747 from Cohesion Biosciences
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GBE1 - MBS8218524 from MyBioSource
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shRNA set against Human GBE1 (NM_000158.3) - SHH299750 from Creative biogene
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Human GBE1 siRNA - orb262249 from Biorbyt
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GBE1 shRNA Plasmid (Human) - CHH1747 from Cohesion Biosciences
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GBE1 miRNA 3'UTR clone - MiUTR3H-09501 from Creative biogene
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