| Gene Symbol |
Hmgcs2
|
| Entrez Gene |
24450
|
| Alt Symbol |
Hmgcs1, Mt3h3mg
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
|
| Other Description |
3-hydroxy-3-methylglutary-Coenzyme A synthase 2|3-hydroxy-3-methylglutaryl coenzyme A synthase|3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)|HMG-CoA synthase|hydroxymethylglutaryl-CoA synthase 2|hydroxymethylglutaryl-CoA synthase, mitochondrial
|
| Swissprots |
P22791
|
| Accessions |
EDL85567 EDL85568 P22791 BC078695 AAH78695 BC083543 AAH83543 M33648 AAA41336 XM_006233002 XP_006233064 NM_173094 NP_775117
|
| Function |
This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
|
| Subcellular Location |
Mitochondrion.
|
| Tissue Specificity |
Liver and kidney.
|
| Top Pathways |
Terpenoid backbone biosynthesis, PPAR signaling pathway, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism
|