PCMT1

Gene Symbol PCMT1
Entrez Gene 5110
Alt Symbol PIMT
Species Human
Gene Type protein-coding
Description protein-L-isoaspartate (D-aspartate) O-methyltransferase
Other Description L-isoaspartyl protein carboxyl methyltransferase|protein L-isoaspartyl/D-aspartyl methyltransferase|protein-L-isoaspartate(D-aspartate) O-methyltransferase|protein-beta-aspartate methyltransferase
Swissprots Q9BQV7 J3KP72 Q16556 A8K109 Q9NP03 Q14661 Q93061 Q9BQV8 Q5VYC1 Q5VYC2 P22061 Q99625 Q96II9
Accessions AAB38386 AAC60639 AAC60640 AAC60641 EAW47786 EAW47787 EAW47788 P22061 AA442100 AI220702 AK098739 AK129778 AK289724 BAF82413 AK304532 BAH14208 AL539512 AW025538 BC007501 AAH07501 BC008748 AAH08748 BC018569 BE262147 BX438393 CA441980 CX786396 D13892 BAA02991 D25545 BAA05028 D25546 BAA05029 D25547 BAA05030 DB478200 DC339361 DC356391 DC421281 HQ448137 ADQ32618 M93008 AAA90934 M93009 AAA90933 XM_011535868 XP_011534170 NM_001252049 NP_001238978 NM_001252050 NP_001238979 NM_001252051 NP_001238980 NM_001252052 NP_001238981 NM_001252053 NP_001238982 NM_005389 NP_005380
Function Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine- binding protein 1, stathmin, beta-synuclein and alpha-synuclein. {ECO:0000250|UniProtKB:P23506}.
Subcellular Location Cytoplasm.

PCMT1 (C-15) - sc-168915 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PCMT1 (C-15): sc-168915. Western blot analysis of PCMT1 expression in Jurkat (A) and Hep G2 (B) whole cell lysates.

PCMT1 (D-24) - sc-133894 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
PCMT1 (D-24): sc-133894. Western blot analysis of PCMT1 expression in Hep G2 whole cell lysate.

PCMT1 (D-E7) - sc-100977 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PCMT1 (D-E7): sc-100977. Western blot analysis of PCMT1 expression in HeLa whole cell lysate.

PCMT1 (N-14) - sc-168916 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PIMT (H-223) - sc-99239 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PIMT (H-223): sc-99239. Western blot analysis of PIMT expression in SW480 nuclear extract (A) and rat testis tissue extract (B).

Anti-PCMT1 antibody - ab97446 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PCMT1 antibody (ab97446) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-PCMT1 antibody - ab192790 from Abcam

Prices $407.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of methanol fixed A431 cells labeling PCMT1 with ab192790 at 1/200 (green). The cells were costained with Hoechst 33342.

Anti-PCMT1 antibody - ab55510 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PCMT1 antibody - ab89185 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PCMT1 antibody (ab89185) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : Jurkat cell lysate

Anti-PCMT1 Antibody (C-Terminus) - LS-C136989 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PCMT1 Antibody (aa1-229, Azide-free) - LS-C328248 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-PCMT1 Antibody (clone 4G9) - LS-C197853 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G9
PCMT1 monoclonal antibody (M01), clone 4G9 Western Blot analysis of PCMT1 expression in PC-12.

Anti-PCMT1 Antibody (aa209-258) - LS-C81275 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.

Anti-PCMT1 Antibody - LS-C334874 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PCMT1 antibody.

Anti-PCMT1 Antibody (aa10-227) IHC-plus™ - LS-B10799 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PCMT1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10799 concentration 7.5 ug/ml.

PCMT1 Antibody - NBP1-85806 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCMT1 Antibody (1D6) - H00005110-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D6
Western Blot: PCMT1 Antibody (1D6) [H00005110-M02] - PCMT1 monoclonal antibody (M02), clone 1D6. Analysis of PCMT1 expression in Raw 264.7.

PCMT1 Antibody - NBP1-33019 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PIMT Antibody - NBP1-92271 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PIMT Antibody [NBP1-92271] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: NTERA-2 Medium

PCMT1 Antibody (4G9) - H00005110-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G9
Western Blot: PCMT1 Antibody (4G9) [H00005110-M01] - PCMT1 monoclonal antibody (M01), clone 4G9 Analysis of PCMT1 expression in PC-12.

PIMT Antibody - NB600-222 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PCMT1 Antibody - NBP2-19731 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCMT1 Antibody [NBP2-19731] - Sample (30 ug of whole cell lysate) A: U87-MG 12% SDS PAGE gel, diluted at 1:1000.

PCMT1 Antibody - H00005110-A02 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

PCMT1 Antibody - H00005110-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

PCMT1 Polyclonal Antibody - bs-6211R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-PCMT1 Polyclonal Antibody, Unconjugated(bs-6211R) at 1:200, followed by conjugation to the secondary antibody and DAB staining
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