Gene Symbol | BAIAP2L1 |
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Entrez Gene | 55971 |
Alt Symbol | IRTKS |
Species | Human |
Gene Type | protein-coding |
Description | BAI1-associated protein 2-like 1 |
Other Description | BAI1-associated protein 2-like protein 1|brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1|insulin receptor tyrosine kinase substrate |
Swissprots | Q9Y2M8 Q75L21 Q9UHR4 Q9H5F5 Q96CV4 Q75L22 A4D268 |
Accessions | AAD20937 AAS07549 AAS07550 EAL23890 EAW76706 EAW76707 Q9UHR4 AF119666 AAF17223 AK027109 AK027142 BAB15671 AK074419 AK124269 AK309936 BC013888 AAH13888 BI560834 BM977002 DA442866 EU832667 ACE87758 EU832746 ACE87078 NM_018842 NP_061330 |
Function | May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. {ECO:0000269|PubMed:17430976, ECO:0000269|PubMed:19366662, ECO:0000269|PubMed:22921828}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19366662}. Note=Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites. |
BAIAP2L1 CRISPR/Cas9 KO Plasmid (h) - sc-406715 from Santa Cruz Biotechnology
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BAIAP2L1 HDR Plasmid (h) - sc-406715-HDR from Santa Cruz Biotechnology
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BAIAP2L1 Double Nickase Plasmid (h) - sc-406715-NIC from Santa Cruz Biotechnology
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BAIAP2L1 Double Nickase Plasmid (h2) - sc-406715-NIC-2 from Santa Cruz Biotechnology
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BAIAP2L1 CRISPR Activation Plasmid (h) - sc-406715-ACT from Santa Cruz Biotechnology
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BAIAP2L1 CRISPR Activation Plasmid (h2) - sc-406715-ACT-2 from Santa Cruz Biotechnology
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BAIAP2L1 Lentiviral Activation Particles (h) - sc-406715-LAC from Santa Cruz Biotechnology
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BAIAP2L1 Lentiviral Activation Particles (h2) - sc-406715-LAC-2 from Santa Cruz Biotechnology
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BAIAP2L1 siRNA (h) - sc-89810 from Santa Cruz Biotechnology
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BAIAP2L1 shRNA Plasmid (h) - sc-89810-SH from Santa Cruz Biotechnology
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BAIAP2L1 shRNA (h) Lentiviral Particles - sc-89810-V from Santa Cruz Biotechnology
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BAIAP2L1 RNAi - H00055971-R04 from Novus Biologicals
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MISSION® esiRNA - EHU027801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3852 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3852 from Sigma-Aldrich
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BAIAP2L1 siRNA (Human) - CRJ1030 from Cohesion Biosciences
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BAIAP2L1 - MBS828506 from MyBioSource
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shRNA set against Human BAIAP2L1 (NM_018842.4) - SHH244762 from Creative biogene
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BAIAP2L1 shRNA Plasmid (Human) - CHJ1030 from Cohesion Biosciences
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BAIAP2L1 miRNA 3'UTR clone - MiUTR3H-12194 from Creative biogene
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