PLA2G16

Gene Symbol	PLA2G16
Entrez Gene	11145
Alt Symbol	AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-1, HREV107-3, HRSL3
Species	Human
Gene Type	protein-coding
Description	phospholipase A2, group XVI
Other Description	Ca-independent phospholipase A1/2|H-rev 107 protein homolog|HRAS-like suppressor 1|HRAS-like suppressor 3|adipose-specific PLA2|adipose-specific phospholipase A2|group XVI phospholipase A1/A2|group XVI phospholipase A2|renal carcinoma antigen NY-REN-65
Swissprots	Q3SYI3 B7XAK5 B2R7Q4 P53816 Q9HDD1
Accessions	EAW74158 EAW74159 EAW74160 P53816 AB030814 BAB08108 AB439591 BAH08749 AF317086 AAL26892 AI374456 AI590735 AK313075 BAG35901 AU099540 AX775893 CAE11646 BC001387 AAH01387 BC103807 AAI03808 BC103808 AAI03809 BG719903 CK003948 DQ892568 ABM83494 DQ895783 ABM86709 X92814 CAA63423 XM_006718426 XP_006718489 XM_011544741 XP_011543043 NM_001128203 NP_001121675 NM_007069 NP_009000
Function	Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O- acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity. {ECO:0000250, ECO:0000269|PubMed:17374643, ECO:0000269|PubMed:19615464}.
Subcellular Location	Cytoplasm. Cytoplasm, perinuclear region {ECO:0000250}. Membrane; Single-pass membrane protein.
Tissue Specificity	Widely expressed. low expression, if any, in hematopoietic cells and thymus. In testis, confined to round spermatids. Expressed in normal ovarian epithelial cells. Down- regulated in some ovarian carcinomas and testicular germ cell tumors. {ECO:0000269|PubMed:11526504, ECO:0000269|PubMed:11973642, ECO:0000269|PubMed:19615464, ECO:0000269|PubMed:9771974}.
Top Pathways	Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism, alpha-Linolenic acid metabolism, Glycerophospholipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HRASLS3 full length protein - ab132613 from Abcam Category Protein Source Wheat germ Species Human

Human HRASLS3 protein fragment - ab152078 from Abcam Category Protein Source E. coli Species Human

Human HRASLS3 protein fragment - ab86922 from Abcam Category Protein Source E. coli Species Human

PLA2G16 / HRASLS3 Antibody Blocking Peptide - LS-E7959 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PLA2G16 / HRASLS3 Antibody Blocking Peptide - LS-E26620 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PLA2G16/HRASLS3 Protein - H00011145-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HRASLS3-Antibody-C-term-Blocking-peptide - BP5747a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HRASLS3/HREV107-3 blocking peptide - GTX88661-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

HRASLS3 Protein (OPPA01808) - OPPA01808 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

Human HRASLS3 protein - orb90147 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 10 μg, 50 μg Source E.coli Species Human

HRAS like suppressor 3 protein - 30R-1233 from Fitzgerald Category Protein Prices $180.00 Sizes 100 µg Source E.coli

HRASLS3 Peptide - AC21-1456-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

HRAS-like suppressor 3 / HRASLS3 (1-133) - AR09145PU-L from Acris Antibodies Category Protein Prices $585.00 Sizes 500 µg Source E. coli Species Human

HRAS-like suppressor 3 / HRASLS3 (1-133) - AR09145PU-N from Acris Antibodies Category Protein Prices $270.00 Sizes 100 µg Source E. coli Species Human

HRAS-like suppressor 3 / HRASLS3 - H00011145-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HRAS-like suppressor 3 / HRASLS3 - H00011145-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HRAS-Like Suppressor 3, Human Recombinant (PLA2G16) - 228-10777-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human HRASLS2 / PLA2G16 - 228-10777-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human HRASLS2 / PLA2G16 - 228-10777-3 from RayBiotech Category Protein Prices $1,950.00 Sizes 3 µg Source Escherichia Coli. Species Human

HRAS-like suppressor3,1-133aa, Human,Recombinant, E.coli - 01-2029 from ARP American Research Products Category Protein Prices $139.00, $299.00, $639.00 Sizes 20 µg, 100 µg, 500 µg Source E.coli Species Human

PLA2G16, Adipose-specific phospholipase A2, Human, Recombinant - 19-CE82 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source E. coli Species Human

PLA2G16 Peptide - 46-856P from ProSci Category Peptide

PLA2G16 fusion protein - ag7188 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PLA2G16 fusion protein - ag6748 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

HRASLS3 Human - ENPS-343 from NeoScientific Category Protein Prices $65.00, $169.00, $2,340.00 Sizes 10 µg, 50 µg, 1 mg Source Escherichia Coli. Species Human

Search more