Gene Symbol | MEPE |
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Entrez Gene | 56955 |
Alt Symbol | OF45 |
Species | Human |
Gene Type | protein-coding |
Description | matrix extracellular phosphoglycoprotein |
Other Description | matrix, extracellular phosphoglycoprotein with ASARM motif (bone)|osteoblast/osteocyte factor 45 |
Swissprots | A8MTA3 F5H5C5 A1A4X9 D2CFR4 Q9NQ76 |
Accessions | ACS37536 EAX06001 EAX06002 EAX06003 Q9NQ76 AF325916 AAK70343 AJ276396 CAB97250 AK075076 BAC11386 AK307774 BC128158 AAI28159 CA436639 DC314534 DC326111 DQ854717 ABI64294 XM_006714278 XP_006714341 NM_001184694 NP_001171623 NM_001184695 NP_001171624 NM_001184696 NP_001171625 NM_001184697 NP_001171626 NM_001291183 NP_001278112 NM_020203 NP_064588 |
Function | Promotes renal phosphate excretion and modulates mineralization. {ECO:0000269|PubMed:14962809}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expressed by osteoblasts. Secreted from oncogenic hypophosphataemic tumors. |
MEPE CRISPR/Cas9 KO Plasmid (h) - sc-403162 from Santa Cruz Biotechnology
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MEPE HDR Plasmid (h) - sc-403162-HDR from Santa Cruz Biotechnology
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MEPE Double Nickase Plasmid (h) - sc-403162-NIC from Santa Cruz Biotechnology
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MEPE Double Nickase Plasmid (h2) - sc-403162-NIC-2 from Santa Cruz Biotechnology
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MEPE CRISPR Activation Plasmid (h) - sc-403162-ACT from Santa Cruz Biotechnology
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MEPE CRISPR Activation Plasmid (h2) - sc-403162-ACT-2 from Santa Cruz Biotechnology
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MEPE Lentiviral Activation Particles (h) - sc-403162-LAC from Santa Cruz Biotechnology
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MEPE Lentiviral Activation Particles (h2) - sc-403162-LAC-2 from Santa Cruz Biotechnology
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MEPE siRNA (h) - sc-75773 from Santa Cruz Biotechnology
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MEPE shRNA Plasmid (h) - sc-75773-SH from Santa Cruz Biotechnology
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MEPE shRNA (h) Lentiviral Particles - sc-75773-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU145601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13209 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13209 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03033 from Sigma-Aldrich
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MEPE siRNA (Human) - CRJ1254 from Cohesion Biosciences
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shRNA set against Human MEPE (NM_020203.3) - SHH340463 from Creative biogene
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MEPE shRNA Plasmid (Human) - CHJ1254 from Cohesion Biosciences
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