| Gene Symbol | Cnot11 |
|---|---|
| Entrez Gene | 52846 |
| Alt Symbol | 2410015L18Rik, C40, D1Bwg0212e |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | CCR4-NOT transcription complex, subunit 11 |
| Other Description | CCR4-NOT transcription complex subunit 11|UPF0760 protein C2orf29 homolog |
| Swissprots | Q9CWN7 Q3TJG9 |
| Accessions | EDL14559 Q9CWN7 AK010503 BAB26988 AK041342 BAC30912 AK086565 AK144692 BAE26018 AK162118 AK167440 BAE39526 BC049091 AAH49091 BC050812 AAH50812 NM_028043 NP_082319 |
| Function | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
D1Bwg0212e siRNA (m) - sc-142800 from Santa Cruz Biotechnology
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D1Bwg0212e shRNA Plasmid (m) - sc-142800-SH from Santa Cruz Biotechnology
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D1Bwg0212e shRNA (m) Lentiviral Particles - sc-142800-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU001691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN29634 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29634 from Sigma-Aldrich
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CNOT11 siRNA (Mouse) - CRM5320 from Cohesion Biosciences
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CNOT11 - MBS8210422 from MyBioSource
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shRNA set against Mouse D1Bwg0212e (NM_028043.2) - SHH274101 from Creative biogene
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CNOT11 shRNA Plasmid (Mouse) - CHM5320 from Cohesion Biosciences
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D1BWG0212E miRNA 3'UTR clone - MiUTR1M-03614 from Creative biogene
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