Gene Symbol | CCDC59 |
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Entrez Gene | 29080 |
Alt Symbol | BR22, HSPC128, TAP26 |
Species | Human |
Gene Type | protein-coding |
Description | coiled-coil domain containing 59 |
Other Description | TTF-1-associated protein 26|TTF-1-associated protein BR2|coiled-coil domain-containing protein 59|thyroid transcription factor 1-associated protein 26 |
Swissprots | Q9P031 Q9H2V5 Q9NW62 |
Accessions | EAW97379 EAW97380 Q9P031 AF161477 AAF29092 AF213377 AAG43569 AK001156 BAA91524 AK225139 AL832749 BC020647 AAH20647 BG538660 BM846580 DA666239 HQ447732 ADQ32217 NM_014167 NP_054886 NR_033192 |
Function | Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC). Enhances homeobox protein Nkx-2.1-activated SFTPB and SFTPC promoter activities. {ECO:0000269|PubMed:12882447, ECO:0000269|PubMed:16630564}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Ubiquitously expressed. In lung, expression is restricted to the alveolar epithelial cells. {ECO:0000269|PubMed:11152647}. |
TAP26 CRISPR/Cas9 KO Plasmid (h) - sc-412024 from Santa Cruz Biotechnology
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TAP26 HDR Plasmid (h) - sc-412024-HDR from Santa Cruz Biotechnology
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TAP26 Double Nickase Plasmid (h) - sc-412024-NIC from Santa Cruz Biotechnology
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TAP26 Double Nickase Plasmid (h2) - sc-412024-NIC-2 from Santa Cruz Biotechnology
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TAP26 CRISPR Activation Plasmid (h) - sc-412024-ACT from Santa Cruz Biotechnology
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TAP26 CRISPR Activation Plasmid (h2) - sc-412024-ACT-2 from Santa Cruz Biotechnology
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TAP26 Lentiviral Activation Particles (h) - sc-412024-LAC from Santa Cruz Biotechnology
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TAP26 Lentiviral Activation Particles (h2) - sc-412024-LAC-2 from Santa Cruz Biotechnology
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TAP26 siRNA (h) - sc-96205 from Santa Cruz Biotechnology
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TAP26 shRNA Plasmid (h) - sc-96205-SH from Santa Cruz Biotechnology
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TAP26 shRNA (h) Lentiviral Particles - sc-96205-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU111861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5542 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5542 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02736 from Sigma-Aldrich
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CCDC59 siRNA (Human) - CRH9174 from Cohesion Biosciences
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CCDC59 - MBS8231065 from MyBioSource
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shRNA set against Human CCDC5 (NM_014167.4) - SHH256741 from Creative biogene
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CCDC59 shRNA Plasmid (Human) - CHH9174 from Cohesion Biosciences
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CCDC59 miRNA 3'UTR clone - MiUTR3H-14365 from Creative biogene
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