| Gene Symbol |
Grm7
|
| Entrez Gene |
81672
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
glutamate receptor, metabotropic 7
|
| Other Description |
mGluR7|metabotropic glutamate receptor 7|metabotropic glutamate receptor mGluR7|metabotropic glutamate receptor subtype 7b
|
| Swissprots |
P35400
|
| Accessions |
EDL91489 P35400 D16817 BAA04092 U06832 AAA20655 X96790 CAA65584 XM_008763199 XP_008761421 NM_031040 NP_112302
|
| Function |
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:8145723, ECO:0000269|PubMed:8288585}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Widely distributed throughout the brain. {ECO:0000269|PubMed:8145723, ECO:0000269|PubMed:8288585}.
|
| Top Pathways |
Glutamatergic synapse, Neuroactive ligand-receptor interaction
|