Gene Symbol | NPPC |
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Entrez Gene | 4880 |
Alt Symbol | CNP, CNP2 |
Species | Human |
Gene Type | protein-coding |
Description | natriuretic peptide C |
Other Description | C-type natriuretic peptide|natriuretic peptide precursor C |
Swissprots | Q4ZG41 P23582 |
Accessions | AAA35703 AAX88912 BAA14351 BAA22154 CAP12670 EAW70984 P23582 BC069120 AAH69120 BC105065 AAI05066 BC105067 AAI05068 HQ419060 ADQ54381 JF420840 ADZ36320 XM_011511245 XP_011509547 NM_024409 NP_077720 |
Function | Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
CNP-53 CRISPR/Cas9 KO Plasmid (h) - sc-403527 from Santa Cruz Biotechnology
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CNP-53 HDR Plasmid (h) - sc-403527-HDR from Santa Cruz Biotechnology
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CNP-53 Double Nickase Plasmid (h) - sc-403527-NIC from Santa Cruz Biotechnology
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CNP-53 Double Nickase Plasmid (h2) - sc-403527-NIC-2 from Santa Cruz Biotechnology
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CNP-53 CRISPR Activation Plasmid (h) - sc-403527-ACT from Santa Cruz Biotechnology
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CNP-53 CRISPR Activation Plasmid (h2) - sc-403527-ACT-2 from Santa Cruz Biotechnology
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CNP-53 Lentiviral Activation Particles (h) - sc-403527-LAC from Santa Cruz Biotechnology
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CNP-53 Lentiviral Activation Particles (h2) - sc-403527-LAC-2 from Santa Cruz Biotechnology
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CNP siRNA (h) - sc-43690 from Santa Cruz Biotechnology
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CNP shRNA Plasmid (h) - sc-43690-SH from Santa Cruz Biotechnology
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CNP shRNA (h) Lentiviral Particles - sc-43690-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN15466 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15466 from Sigma-Aldrich
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NPPC siRNA (Human) - CRH3241 from Cohesion Biosciences
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shRNA set against Human NPPC (NM_024409.2) - SHH354380 from Creative biogene
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Human NPPC siRNA - orb263743 from Biorbyt
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NPPC shRNA Plasmid (Human) - CHH3241 from Cohesion Biosciences
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NPPC miRNA 3'UTR clone - MiUTR4H-TG06105 from Creative biogene
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