| Gene Symbol |
DCAF6
|
| Entrez Gene |
55827
|
| Alt Symbol |
1200006M05Rik, ARCAP, IQWD1, MSTP055, NRIP, PC326
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DDB1 and CUL4 associated factor 6
|
| Other Description |
DDB1- and CUL4-associated factor 6|IQ motif and WD repeat-containing protein 1|IQ motif and WD repeats 1|androgen receptor complex-associated protein|nuclear receptor interaction protein
|
| Swissprots |
Q8TB19 Q8IXH3 A2A295 Q58WW2 B4DNB8 Q7L8I0
|
| Accessions |
EAW90808 EAW90809 EAW90810 EAW90811 EAW90812 Q58WW2 AF116725 AAO15301 AF124434 AF150734 AAF67474 AK000984 AK093970 AK226181 AK297847 BAG60180 AL136738 CAB66672 AY766164 AAX09330 BC025262 AAH25262 BM822167 BQ028917 CA310484 DA128283 DQ768089 ABG76793 DQ892143 ABM83069 DQ895337 ABM86263 XM_005245331 XP_005245388 XM_005245332 XP_005245389 XM_005245333 XP_005245390 XM_011509767 XP_011508069 XR_921892 XR_921893 NM_001017977 NP_001017977 NM_001198956 NP_001185885 NM_001198957 NP_001185886 NM_018442 NP_060912
|
| Function |
Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000269|PubMed:15784617, ECO:0000269|PubMed:16949367, ECO:0000269|PubMed:16964240}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:15784617}.
|
| Tissue Specificity |
Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland. {ECO:0000269|PubMed:15784617}.
|
