Gene Symbol |
NT5E
|
Entrez Gene |
4907
|
Alt Symbol |
CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
5'-nucleotidase, ecto (CD73)
|
Other Description |
5'-NT|5'-nucleotidase|Purine 5-Prime-Nucleotidase|ecto-5'-nucleotidase
|
Swissprots |
P21589 Q5W116 B3KQI8 O75520
|
Accessions |
AAA96950 AAC98672 AAQ21035 CAF86213 CDM22274 EAW48634 EAW48635 EAW48636 P21589 AK075008 BAG52050 AK075083 BAG52063 AK314661 BAG37219 BC015940 AAH15940 BC065937 AAH65937 BQ019358 DA574510 DQ186653 ABA39834 X55740 CAA39271 NM_001204813 NP_001191742 NM_002526 NP_002517
|
Function |
Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. {ECO:0000269|PubMed:21933152}.
|
Subcellular Location |
Cell membrane; Lipid-anchor, GPI-anchor.
|
Top Pathways |
Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism
|