Gene Symbol | ATP5L |
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Entrez Gene | 10632 |
Alt Symbol | ATP5JG |
Species | Human |
Gene Type | protein-coding |
Description | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G |
Other Description | ATP synthase g chain, mitochondrial|ATP synthase subunit g, mitochondrial|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G|ATP synthase, H+ transporting, mitochondrial F1F0, subunit g|ATPase subunit G|F1F0-type ATP synthase subunit g|F1Fo-ATP synthase complex Fo membrane domain g subunit |
Swissprots | Q96BV6 A8K0K3 Q9UBZ7 O75964 |
Accessions | EAW67376 O75964 AA258888 AF070655 AAD20961 AF087846 AAP97159 AF092124 AAC61597 AI337729 AK289568 BAF82257 AL050277 CAB43378 AM393064 CAL37942 AM393513 CAL38390 BC015128 AAH15128 BC070165 AAH70165 BU953217 CR533494 CAG38525 CR542211 CAG47007 NM_006476 NP_006467 NR_033759 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. |
Subcellular Location | Mitochondrion. Mitochondrion inner membrane. |
Top Pathways | Oxidative phosphorylation |
ATP5L CRISPR/Cas9 KO Plasmid (h) - sc-411494 from Santa Cruz Biotechnology
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ATP5L HDR Plasmid (h) - sc-411494-HDR from Santa Cruz Biotechnology
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ATP5L Double Nickase Plasmid (h) - sc-411494-NIC from Santa Cruz Biotechnology
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ATP5L Double Nickase Plasmid (h2) - sc-411494-NIC-2 from Santa Cruz Biotechnology
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ATP5L CRISPR Activation Plasmid (h) - sc-411494-ACT from Santa Cruz Biotechnology
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ATP5L CRISPR Activation Plasmid (h2) - sc-411494-ACT-2 from Santa Cruz Biotechnology
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ATP5L Lentiviral Activation Particles (h) - sc-411494-LAC from Santa Cruz Biotechnology
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ATP5L Lentiviral Activation Particles (h2) - sc-411494-LAC-2 from Santa Cruz Biotechnology
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ATP5L siRNA (h) - sc-97057 from Santa Cruz Biotechnology
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ATP5L shRNA Plasmid (h) - sc-97057-SH from Santa Cruz Biotechnology
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ATP5L shRNA (h) Lentiviral Particles - sc-97057-V from Santa Cruz Biotechnology
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ATP5L RNAi - H00010632-R01 from Novus Biologicals
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MISSION® esiRNA - EHU136341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3709 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3709 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06435 from Sigma-Aldrich
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ATP5L siRNA (Human) - CRH7243 from Cohesion Biosciences
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ATP5L - MBS8218255 from MyBioSource
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shRNA set against Human ATP5L (NM_006476.4) - SHH242890 from Creative biogene
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Human ATP5L siRNA - orb267745 from Biorbyt
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ATP5L shRNA Plasmid (Human) - CHH7243 from Cohesion Biosciences
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ATP5L miRNA 3'UTR clone - MiUTR1H-00703 from Creative biogene
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