Tnc

Gene Symbol Tnc
Entrez Gene 21923
Alt Symbol AI528729, C130033P17Rik, Hxb, TN, TN-C, Ten, cytotactin, tenascin-C
Species Mouse
Gene Type protein-coding
Description tenascin C
Other Description hexabrachion|tenascin|tnc
Swissprots Q80YX1 Q80YX2 Q64706
Accessions EDL31088 EDL31089 Q80YX1 AJ236880 CAB44238 AK040167 BAC30529 AK048765 AK085667 BC117979 AAI17980 BC117980 AAI17981 BU614130 BY300535 CB521403 CD352874 CF531007 CN664449 CN692948 CX568603 D90343 BAA14355 X56304 CAA39751 X80281 XM_006537774 XP_006537837 XM_006537775 XP_006537838 XM_006537776 XP_006537839 XM_006537777 XP_006537840 NM_011607 NP_035737
Function Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth when provided to neurons in culture. May play a role in supporting the growth of epithelial tumors. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. {ECO:0000250|UniProtKB:P24821, ECO:0000269|PubMed:16553788}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity High levels of isoform 2 in lung and brain of newborn mice. High levels of isoform 5 in thymus, moderate levels in brain of newborn and adult mice. Low level of isoform 2 in adult brain. {ECO:0000269|PubMed:1717349}.
Top Pathways Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway, MicroRNAs in cancer

Tenascin-C CRISPR/Cas9 KO Plasmid (m) - sc-423430 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Tenascin-C HDR Plasmid (m) - sc-423430-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Tenascin-C Double Nickase Plasmid (m) - sc-423430-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Tenascin-C Double Nickase Plasmid (m2) - sc-423430-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Tenascin-C CRISPR Activation Plasmid (m) - sc-423430-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Tenascin-C CRISPR Activation Plasmid (m2) - sc-423430-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Tenascin-C Lentiviral Activation Particles (m) - sc-423430-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Tenascin-C Lentiviral Activation Particles (m2) - sc-423430-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Tenascin-C siRNA (m) - sc-43187 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Tenascin-C shRNA Plasmid (m) - sc-43187-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Tenascin-C shRNA (m) Lentiviral Particles - sc-43187-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU079621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN43214 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND43214 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TNC siRNA (Mouse) - CRM4172 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

TNC - MBS8235441 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse TNC (NM_011607.3) - SHH431728 from Creative biogene

Category siRNA
Species Reactivities Mouse

Tenascin-C CRISPR/Cas9 KO Plasmid (m2) - sc-423430-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Tenascin-C HDR Plasmid (m2) - sc-423430-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Mouse TNC siRNA - orb283648 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

TNC shRNA Plasmid (Mouse) - CHM4172 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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