| Gene Symbol |
Galnt7
|
| Entrez Gene |
29750
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
polypeptide N-acetylgalactosaminyltransferase 7
|
| Other Description |
N-acetylgalactosaminyltransferase 7|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)|galNAc-T7|polypeptide GalNAc transferase 7|pp-GaNTase 7|protein-UDP acetylgalactosaminyltransferase 7
|
| Swissprots |
Q9R0C5
|
| Accessions |
EDL87173 EDL87174 Q9R0C5 AF076167 AAC99426 XM_006253083 XP_006253145 NM_022926 NP_075215
|
| Function |
Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in sublingual gland. Expressed at lower level in stomach, small intestiine and colon. {ECO:0000269|PubMed:10488133}.
|
| Top Pathways |
Mucin type O-Glycan biosynthesis
|