Gene Symbol | LUC7L3 |
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Entrez Gene | 51747 |
Alt Symbol | CRA, CREAP-1, CROP, LUC7A, OA48-18, hLuc7A |
Species | Human |
Gene Type | protein-coding |
Description | LUC7-like 3 (S. cerevisiae) |
Other Description | CRE-associated protein 1|cAMP regulatory element-associated protein 1|cisplatin resistance associated overexpressed protein|cisplatin resistance-associated overexpressed protein|cisplatin resistance-associated-overexpressed protein|luc7-like protein 3|okadaic acid-inducible phosphoprotein OA48-18 |
Swissprots | D3DTY1 Q9P2S7 O95232 Q9NUY0 Q6PHR9 B3KN54 |
Accessions | EAW94583 EAW94584 EAW94585 EAW94586 EAW94587 O95232 AF069250 AAC79807 AF147357 AK001925 BAA91981 AK023672 BAG51216 AK027723 AK225980 AK290540 BAF83229 AK295983 BAG58758 AL050121 BC002925 AAH02925 BC047043 AAH47043 BC056409 AAH56409 BC061896 BC156954 AAI56955 BG213545 CN271700 DA231851 DQ013876 AAY26238 XM_005257448 XP_005257505 XM_005257449 XP_005257506 XM_005257450 XP_005257507 XM_005257452 XP_005257509 XM_005257454 XP_005257511 XM_005257455 XP_005257512 XM_006721943 XP_006722006 NM_006107 NP_006098 NM_016424 NP_057508 |
Function | Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. {ECO:0000269|PubMed:16462885}. |
Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:10631324, ECO:0000269|PubMed:12565863}. Note=The subnuclear localization is affected by cisplatin. |
Tissue Specificity | Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung. {ECO:0000269|PubMed:10631324, ECO:0000269|PubMed:16462885}. |
CROP CRISPR/Cas9 KO Plasmid (h) - sc-412243 from Santa Cruz Biotechnology
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CROP HDR Plasmid (h) - sc-412243-HDR from Santa Cruz Biotechnology
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CROP Double Nickase Plasmid (h) - sc-412243-NIC from Santa Cruz Biotechnology
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CROP Double Nickase Plasmid (h2) - sc-412243-NIC-2 from Santa Cruz Biotechnology
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CROP CRISPR Activation Plasmid (h) - sc-412243-ACT from Santa Cruz Biotechnology
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CROP CRISPR Activation Plasmid (h2) - sc-412243-ACT-2 from Santa Cruz Biotechnology
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CROP Lentiviral Activation Particles (h) - sc-412243-LAC from Santa Cruz Biotechnology
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CROP Lentiviral Activation Particles (h2) - sc-412243-LAC-2 from Santa Cruz Biotechnology
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CROP siRNA (h) - sc-93573 from Santa Cruz Biotechnology
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CROP shRNA Plasmid (h) - sc-93573-SH from Santa Cruz Biotechnology
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CROP shRNA (h) Lentiviral Particles - sc-93573-V from Santa Cruz Biotechnology
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CROP RNAi - H00051747-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN12827 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12827 from Sigma-Aldrich
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LUC7L3 siRNA (Human) - CRH9930 from Cohesion Biosciences
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CROP RNAi - H00051747-R01 from Novus Biologicals
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shRNA set against Human LUC7L3 (NM_006107.3) - SHH335603 from Creative biogene
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Human LUC7L3 siRNA - orb270432 from Biorbyt
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LUC7L3 shRNA Plasmid (Human) - CHH9930 from Cohesion Biosciences
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LUC7L3 miRNA 3'UTR clone - MiUTR3H-10606 from Creative biogene
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LUC7L3 miRNA 3'UTR clone - MiUTR4H-TG05225 from Creative biogene
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