| Gene Symbol |
Creb3l1
|
| Entrez Gene |
362165
|
| Alt Symbol |
Oasis
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
cAMP responsive element binding protein 3-like 1
|
| Other Description |
cAMP-responsive element-binding protein 3-like protein 1|cyclic AMP-responsive element-binding protein 3-like protein 1|old astrocyte specifically-induced substance
|
| Swissprots |
Q66HA2
|
| Accessions |
EDL79555 EDL79556 Q66HA2 BC081951 AAH81951 XM_006234584 XP_006234646 NM_001005562 NP_001005562
|
| Function |
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system. May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Top Pathways |
cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway
|