Gene Symbol | MYF5 |
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Entrez Gene | 4617 |
Alt Symbol | bHLHc2 |
Species | Human |
Gene Type | protein-coding |
Description | myogenic factor 5 |
Other Description | class C basic helix-loop-helix protein 2|myf-5 |
Swissprots | Q6ISR9 P13349 |
Accessions | AAA69824 CAI58664 CAI61684 EAW97368 P13349 BC069373 AAH69373 BP231293 BT019399 AAV38206 BX089431 X14894 CAA33025 NM_005593 NP_005584 |
Function | Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. |
Subcellular Location | Nucleus. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells |
Myf-5 CRISPR/Cas9 KO Plasmid (h) - sc-400449 from Santa Cruz Biotechnology
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Myf-5 HDR Plasmid (h) - sc-400449-HDR from Santa Cruz Biotechnology
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Myf-5 Double Nickase Plasmid (h) - sc-400449-NIC from Santa Cruz Biotechnology
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Myf-5 Double Nickase Plasmid (h2) - sc-400449-NIC-2 from Santa Cruz Biotechnology
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Myf-5 CRISPR Activation Plasmid (h) - sc-400449-ACT from Santa Cruz Biotechnology
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Myf-5 CRISPR Activation Plasmid (h2) - sc-400449-ACT-2 from Santa Cruz Biotechnology
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Myf-5 Lentiviral Activation Particles (h) - sc-400449-LAC from Santa Cruz Biotechnology
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Myf-5 Lentiviral Activation Particles (h2) - sc-400449-LAC-2 from Santa Cruz Biotechnology
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Myf-5 siRNA (h) - sc-35988 from Santa Cruz Biotechnology
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Myf-5 shRNA Plasmid (h) - sc-35988-SH from Santa Cruz Biotechnology
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Myf-5 shRNA (h) Lentiviral Particles - sc-35988-V from Santa Cruz Biotechnology
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MYF-5 RNAi - H00004617-R01 from Novus Biologicals
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MISSION® esiRNA - EHU025991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14810 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14810 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05397 from Sigma-Aldrich
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MYF5 siRNA (Human) - CRH3045 from Cohesion Biosciences
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shRNA set against Human MYF5 (NM_005593.2) - SHH347668 from Creative biogene
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Myf-5 CRISPR/Cas9 KO Plasmid (h2) - sc-400449-KO-2 from Santa Cruz Biotechnology
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Myf-5 HDR Plasmid (h2) - sc-400449-HDR-2 from Santa Cruz Biotechnology
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MYF5 shRNA Plasmid (Human) - CHH3045 from Cohesion Biosciences
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MYF5 miRNA 3'UTR clone - MiUTR1H-06562 from Creative biogene
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