| Gene Symbol |
F5
|
| Entrez Gene |
2153
|
| Alt Symbol |
FVL, PCCF, RPRGL1, THPH2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
coagulation factor V (proaccelerin, labile factor)
|
| Other Description |
activated protein c cofactor|coagulation factor V|coagulation factor V jinjiang A2 domain|factor V Leiden|proaccelerin, labile factor
|
| Swissprots |
Q8WWQ6 Q2EHR5 Q5R347 Q14285 A8K6E8 Q5R346 Q6UPU6 P12259
|
| Accessions |
AAB59401 AAF32515 AAG30113 AAL09164 AAN12307 AAQ55063 AAX73254 AAY85741 ABC75245 ABC96776 ABC96777 ABC96778 ABD23003 ACV32684 ACV32685 ACV32686 ACV32687 ACV32688 AEC12481 EAW90849 P12259 AJ297254 CAC82572 AJ297255 CAC82573 AK226079 AK291613 BAF84302 AK300469 BAG62188 AU279657 BC111461 AAI11462 BC111588 AAI11589 BC111929 AAI11930 CA395604 CB164139 DB182033 M14335 AAB59532 M16967 AAA52424 M94010 AAA52416 NM_000130 NP_000121
|
| Function |
Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.
|
| Subcellular Location |
Secreted {ECO:0000250}.
|
| Tissue Specificity |
Plasma.
|
| Top Pathways |
Complement and coagulation cascades
|