Gene Symbol |
NOMO2
|
Entrez Gene |
283820
|
Alt Symbol |
Nomo, PM5
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
NODAL modulator 2
|
Other Description |
nodal modulator 2|pM5 protein 2|pM5 protein, centromeric copy
|
Swissprots |
Q4G177 Q5JPE7
|
Accessions |
Q5JPE7 AK225803 AL512687 CAC21645 AL832855 CAI46162 BC028389 AAH28389 BC041131 AAH41131 BG830626 NM_001004060 NP_001004060 NM_173614 NP_775885
|
Function |
May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN. {ECO:0000250}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:15257293, ECO:0000269|PubMed:17261586}; Single-pass membrane protein {ECO:0000269|PubMed:15257293, ECO:0000269|PubMed:17261586}.
|
Tissue Specificity |
Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart. {ECO:0000269|PubMed:15257293}.
|