Gene Symbol | BCS1L |
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Entrez Gene | 617 |
Alt Symbol | BCS, BCS1, BJS, FLNMS, GRACILE, Hs.6719, MC3DN1, PTD, h-BCS |
Species | Human |
Gene Type | protein-coding |
Description | BC1 (ubiquinol-cytochrome c reductase) synthesis-like |
Other Description | BCS1-like protein|h-BCS1|mitochondrial chaperone BCS1|mitochondrial complex III assembly |
Swissprots | Q9Y276 Q7Z2V7 B3KTW9 |
Accessions | AAK29417 AAN05490 AAY24033 EAW70634 EAW70635 EAW70636 EAW70637 EAW70638 EAW70639 EAW70640 Q9Y276 AF026849 AAD08638 AF038195 AAB97365 AK096210 BAG53231 AK223518 BAD97238 AK289363 BAF82052 BC000416 AAH00416 BC007500 AAH07500 BX571752 CAE11877 DA540458 DA613959 DQ891877 ABM82803 DQ895064 ABM85990 EF672347 ABV24964 EU832513 ACE87685 EU832594 ACE86996 XM_005246747 XP_005246804 XM_005246748 XP_005246805 XM_005246749 XP_005246806 XM_006712678 XP_006712741 XM_011511587 XP_011509889 XM_011511588 XP_011509890 XR_427105 NM_001079866 NP_001073335 NM_001257342 NP_001244271 NM_001257343 NP_001244272 NM_001257344 NP_001244273 NM_004328 NP_004319 |
Function | Chaperone necessary for the assembly of mitochondrial respiratory chain complex III. Plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. {ECO:0000269|PubMed:18628306}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:18628306, ECO:0000269|PubMed:9878253}; Single- pass membrane protein {ECO:0000269|PubMed:18628306, ECO:0000269|PubMed:9878253}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:9878253}. |
BCS1L CRISPR/Cas9 KO Plasmid (h) - sc-408615 from Santa Cruz Biotechnology
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BCS1L HDR Plasmid (h) - sc-408615-HDR from Santa Cruz Biotechnology
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BCS1L Double Nickase Plasmid (h) - sc-408615-NIC from Santa Cruz Biotechnology
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BCS1L Double Nickase Plasmid (h2) - sc-408615-NIC-2 from Santa Cruz Biotechnology
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BCS1L CRISPR Activation Plasmid (h) - sc-408615-ACT from Santa Cruz Biotechnology
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BCS1L CRISPR Activation Plasmid (h2) - sc-408615-ACT-2 from Santa Cruz Biotechnology
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BCS1L Lentiviral Activation Particles (h) - sc-408615-LAC from Santa Cruz Biotechnology
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BCS1L Lentiviral Activation Particles (h2) - sc-408615-LAC-2 from Santa Cruz Biotechnology
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BCS1L siRNA (h) - sc-72637 from Santa Cruz Biotechnology
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BCS1L shRNA Plasmid (h) - sc-72637-SH from Santa Cruz Biotechnology
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BCS1L shRNA (h) Lentiviral Particles - sc-72637-V from Santa Cruz Biotechnology
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BCS1L RNAi - H00000617-R01 from Novus Biologicals
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BCS1L RNAi - H00000617-R02 from Novus Biologicals
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MISSION® esiRNA - EHU073981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3933 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3933 from Sigma-Aldrich
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BCS1L siRNA (Human) - CRH0421 from Cohesion Biosciences
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BCS1L - MBS8241346 from MyBioSource
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shRNA set against Human BCS1L (NM_004328.4) - SHH246178 from Creative biogene
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shRNA set against Human BCS1L(NM_001079866.1) - SHG098479 from Creative biogene
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Human BCS1L siRNA - orb260923 from Biorbyt
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BCS1L shRNA Plasmid (Human) - CHH0421 from Cohesion Biosciences
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BCS1L miRNA 3'UTR clone - MiUTR1H-00861 from Creative biogene
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BCS1L miRNA 3'UTR clone - MiUTR3H-06153 from Creative biogene
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