Gene Symbol | Soat1 |
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Entrez Gene | 20652 |
Alt Symbol | 8430426K15Rik, ACAT-1, AW550831, Acact, ald, hid |
Species | Mouse |
Gene Type | protein-coding |
Description | sterol O-acyltransferase 1 |
Other Description | acyl coenzyme A:cholesterol acyltransferase 1|acyl-coenzyme A:cholesterol acyltransferase 1|adrenocortical lipid depletion|cholesterol acyltransferase 1 |
Swissprots | Q64180 Q61263 Q5XK32 |
Accessions | EDL39380 Q61263 AK018442 AK052299 BAC34925 AK054149 AK087210 AK142486 BAE25081 AK159393 BAE35047 AK159529 BAE35158 AK160017 BAE35563 AK194774 AK213760 BC083092 AAH83092 CJ164331 DQ903181 ABI81497 S81092 AAB36050 U06668 XM_006496719 XP_006496782 XM_011238778 XP_011237080 NM_009230 NP_033256 |
Function | Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000269|PubMed:11071899}. |
Top Pathways | Steroid biosynthesis |
SOAT1 CRISPR/Cas9 KO Plasmid (m) - sc-423068 from Santa Cruz Biotechnology
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SOAT1 HDR Plasmid (m) - sc-423068-HDR from Santa Cruz Biotechnology
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SOAT1 Double Nickase Plasmid (m) - sc-423068-NIC from Santa Cruz Biotechnology
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SOAT1 Double Nickase Plasmid (m2) - sc-423068-NIC-2 from Santa Cruz Biotechnology
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SOAT1 CRISPR Activation Plasmid (m) - sc-423068-ACT from Santa Cruz Biotechnology
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SOAT1 CRISPR Activation Plasmid (m2) - sc-423068-ACT-2 from Santa Cruz Biotechnology
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SOAT1 Lentiviral Activation Particles (m) - sc-423068-LAC from Santa Cruz Biotechnology
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SOAT1 Lentiviral Activation Particles (m2) - sc-423068-LAC-2 from Santa Cruz Biotechnology
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SOAT1 siRNA (m) - sc-29625 from Santa Cruz Biotechnology
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SOAT1 shRNA Plasmid (m) - sc-29625-SH from Santa Cruz Biotechnology
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SOAT1 shRNA (m) Lentiviral Particles - sc-29625-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU078711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN41798 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND41798 from Sigma-Aldrich
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SOAT1 siRNA (Mouse) - CRM3840 from Cohesion Biosciences
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SOAT1 - MBS8204212 from MyBioSource
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shRNA set against Mouse SOAT1 (NM_009230.3) - SHH414908 from Creative biogene
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shRNA set against Mouse Soat1(NM_009230.3) - SHL024042 from Creative biogene
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SOAT1 shRNA Plasmid (Mouse) - CHM3840 from Cohesion Biosciences
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SOAT1 miRNA 3'UTR clone - MiUTR1M-11072 from Creative biogene
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