Gene Symbol | NLRP7 |
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Entrez Gene | 199713 |
Alt Symbol | CLR19.4, HYDM, NALP7, NOD12, PAN7, PYPAF3 |
Species | Human |
Gene Type | protein-coding |
Description | NLR family, pyrin domain containing 7 |
Other Description | NACHT, LRR and PYD containing protein 7|NACHT, LRR and PYD domains-containing protein 7|NACHT, leucine rich repeat and PYD containing 7|PYRIN-containing Apaf1-like protein 3|nucleotide-binding oligomerization domain protein 12|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7 |
Swissprots | Q7RTR1 Q32MH8 E9PE16 Q8WX94 |
Accessions | EAW72313 EAW72314 EAW72315 EAW72316 Q8WX94 AF464765 AAL69963 AK298630 BAG60806 AK302655 BAG63894 AK313964 AY154462 AAO18158 BC109124 AAI09125 BC109125 AAI09126 BK001113 DAA01246 BX363944 DC425389 XM_006723075 XP_006723138 XM_006723076 XP_006723139 XM_006725637 XP_006725700 XM_006725638 XP_006725701 XM_006725764 XP_006725827 XM_006725765 XP_006725828 XM_006725953 XP_006726016 XM_006725954 XP_006726017 XM_006726052 XP_006726115 XM_006726053 XP_006726116 XM_006726150 XP_006726213 XM_006726151 XP_006726214 XM_006726190 XP_006726253 XM_006726191 XP_006726254 XM_006726307 XP_006726370 XM_006726308 XP_006726371 XM_011526596 XP_011524898 XM_011526597 XP_011524899 XM_011526598 XP_011524900 XM_011526599 XP_011524901 XM_011526600 XP_011524902 XM_011526601 XP_011524903 XM_011547105 XP_011545407 XM_011547106 XP_011545408 XM_011547107 XP_011545409 XM_011547108 XP_011545410 XM_011547109 XP_011545411 XM_011547110 XP_011545412 XM_011547513 XP_011545815 XM_011547514 XP_011545816 XM_011547515 XP_011545817 XM_011547516 XP_011545818 XM_011547762 XP_011546064 XM_011547763 XP_011546065 XM_011547764 XP_011546066 XM_011547765 XP_011546067 XM_011547766 XP_011546068 XM_011547767 XP_011546069 XM_011547963 XP_011546265 XM_011547964 XP_011546266 XM_011547965 XP_011546267 XM_011547966 XP_011546268 XM_011547967 XP_011546269 XM_011547968 XP_011546270 XM_011547969 XP_011546271 XM_011547970 XP_011546272 XM_011548142 XP_011546444 XM_011548143 XP_011546445 XM_011548144 XP_011546446 XM_011548145 XP_011546447 XM_011548146 XP_011546448 XM_011548147 XP_011546449 XM_011548335 XP_011546637 XM_011548336 XP_011546638 XM_011548337 XP_011546639 XM_011548338 XP_011546640 XM_011548339 XP_011546641 XM_011548340 XP_011546642 XM_011548547 XP_011546849 XM_011548548 XP_011546850 XM_011548549 XP_011546851 XM_011548550 XP_011546852 XM_011548551 XP_011546853 XM_011548552 XP_011546854 XM_011548598 XP_011546900 XM_011548599 XP_011546901 XM_011548600 XP_011546902 XM_011548601 XP_011546903 XM_011548602 XP_011546904 XM_011548603 XP_011546905 XM_011548604 XP_011546906 XM_011548605 XP_011546907 XM_011548691 XP_011546993 XM_011548692 XP_011546994 XM_011548693 XP_011546995 XM_011548694 XP_011546996 XM_011548695 XP_011546997 XM_011548696 XP_011546998 XR_935761 XR_952189 XR_952524 XR_952756 XR_952908 XR_952986 XR_953060 XR_953129 XR_953147 XR_953170 NM_001127255 NP_001120727 NM_139176 NP_631915 NM_206828 NP_996611 |
Function | Inhibits CASP1/caspase-1-dependent IL1B secretion. {ECO:0000269|PubMed:15817483}. |
Tissue Specificity | Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle. {ECO:0000269|PubMed:15817483, ECO:0000269|PubMed:16462743}. |
NALP7 CRISPR/Cas9 KO Plasmid (h) - sc-403262 from Santa Cruz Biotechnology
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NALP7 HDR Plasmid (h) - sc-403262-HDR from Santa Cruz Biotechnology
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NALP7 Double Nickase Plasmid (h) - sc-403262-NIC from Santa Cruz Biotechnology
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NALP7 Double Nickase Plasmid (h2) - sc-403262-NIC-2 from Santa Cruz Biotechnology
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NALP7 CRISPR Activation Plasmid (h) - sc-403262-ACT from Santa Cruz Biotechnology
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NALP7 CRISPR Activation Plasmid (h2) - sc-403262-ACT-2 from Santa Cruz Biotechnology
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NALP7 Lentiviral Activation Particles (h) - sc-403262-LAC from Santa Cruz Biotechnology
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NALP7 Lentiviral Activation Particles (h2) - sc-403262-LAC-2 from Santa Cruz Biotechnology
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NALP7 siRNA (h) - sc-61149 from Santa Cruz Biotechnology
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NALP7 shRNA Plasmid (h) - sc-61149-SH from Santa Cruz Biotechnology
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NALP7 shRNA (h) Lentiviral Particles - sc-61149-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN15359 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15359 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00863 from Sigma-Aldrich
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NLRP7 siRNA (Human) - CRJ6213 from Cohesion Biosciences
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shRNA set against Human NLRP7 (NM_139176.3) - SHH353044 from Creative biogene
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Human NLRP7 siRNA - orb276714 from Biorbyt
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NLRP7 shRNA Plasmid (Human) - CHJ6213 from Cohesion Biosciences
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NLRP7 miRNA 3'UTR clone - MiUTR4H-TG06038 from Creative biogene
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