| Gene Symbol | HNF4A |
|---|---|
| Entrez Gene | 3172 |
| Alt Symbol | FRTS4, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14 |
| Species | Human |
| Gene Type | protein-coding |
| Description | hepatocyte nuclear factor 4, alpha |
| Other Description | HNF4alpha10/11/12|TCF-14|hepatic nuclear factor 4 alpha|hepatocyte nuclear factor 4-alpha|nuclear receptor subfamily 2 group A member 1|transcription factor 14|transcription factor HNF-4 |
| Swissprots | Q9NQH0 Q6B4V6 Q14540 P41235 A5JW41 Q92655 O00723 B2RPP8 Q6B4V5 Q6B4V7 Q92654 Q92653 Q5QPB8 Q99864 O00659 |
| Accessions | AAB48082 AAB48083 AAM34296 ABQ52204 EAW75921 EAW75922 EAW75923 EAW75924 EAW75925 P41235 AB307703 BAH02294 AK096973 AW134564 AW935533 AY680696 AAT91237 AY680697 AAT91238 AY680698 AAT91239 BC137539 AAI37540 BC137540 AAI37541 BP274413 CB163637 FJ608822 ACM50922 HQ692860 ADZ17371 HQ692868 ADZ17379 HQ692869 ADZ17380 X76930 CAA54248 X87870 CAA61133 X87871 CAA61134 X87872 CAA61135 Z49825 CAA89989 XM_005260407 XP_005260464 XM_011528797 XP_011527099 XM_011528798 XP_011527100 NM_000457 NP_000448 NM_001030003 NP_001025174 NM_001030004 NP_001025175 NM_001258355 NP_001245284 NM_001287182 NP_001274111 NM_001287183 NP_001274112 NM_001287184 NP_001274113 NM_175914 NP_787110 NM_178849 NP_849180 NM_178850 NP_849181 |
| Function | Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine. |
| Subcellular Location | Nucleus. |
| Top Pathways | Maturity onset diabetes of the young, AMPK signaling pathway |